Gene: AT5G46210 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT5G46210
Transcript Identifier
AT5G46210.1
Gene Type
Coding gene
Location
Chr5 : 18731569-18736653 : negative

Family

Gene family
HOM04M000392
(290 genes in 29 species)
specific family
Subfamily
ORTHO04M005522
(40 genes in 29 species)
specific family

Descriptions

Description
cullin4
Curated Summary
Arabidopsis CULLIN4 (CUL4) forms an E3 ubiquitin ligase with the CDD complex and a common catalytic subunit RBX1 in mediating light control of development. This CUL4-based E3 ligase is essential for the repression of photomorphogenesis. The partial loss of CUL4 function resulted in a constitutive photomorphogenic phenotype with respect to morphogenesis and light-regulated gene expression. CUL4 exhibits a synergistic genetic interaction with COP10 and DET1.
Show more...

Identifiers

Type Value
AliasATCUL4
symbolCUL4
tidAT5G46210.1
UniProtQ8LGH4

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006511 IEAInterProubiquitin-dependent protein catabolic process
GO:0009738 IEAUniProtabscisic acid-activated signaling pathway1
GO:0042787 IBAUniProtprotein ubiquitination involved in ubiquitin-dependent protein catabolic process1
GO:0009640 IMPUniProtphotomorphogenesis1
GO:0048366 IMPUniProtleaf development1
GO:0000209 IDAUniProtprotein polyubiquitination1
GO:0009908 IMPUniProtflower development1
GO:0010100 IMPUniProtnegative regulation of photomorphogenesis1
GO:0048367 IMPUniProtshoot system development1
GO:0009755 IMPUniProthormone-mediated signaling pathway1
GO:0010154 IMPUniProtfruit development1
GO:0010182 IMPUniProtsugar mediated signaling pathway1
GO:0048825 IMPUniProtcotyledon development1
GO:0006281 IMPUniProtDNA repair1
GO:0048575 IMPUniProtshort-day photoperiodism, flowering1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0031625 IBA, IEA, UniProtubiquitin protein ligase binding1
GO:0061630 IBAGene Ontologyubiquitin protein ligase activity1
GO:0005515 IPIGene Ontologyprotein binding1 2

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634 IDA, ISM, UniProtnucleus1 2
GO:0080008 IPIUniProtCul4-RING E3 ubiquitin ligase complex1
GO:0000151 IPIUniProtubiquitin ligase complex1
GO:0005829 IDAUniProtcytosol1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR011991Winged helix-turn-helix DNA-binding domain
IPR019559Cullin protein, neddylation domain
IPR001373Cullin, N-terminal
IPR016158Cullin homology
IPR016159Cullin repeat-like-containing domain

Mapman id Description
19.2.2.8.3.1.Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.CUL4-DDB1 ubiquitination complexes.scaffold component CUL4
26.1.1.3.1.External stimuli response.light.red/far red light.CUL4-DDB1 ubiquitination complex.scaffold component (CUL4)
No SignalP domains detected for this gene.