Gene: AT5G45340 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT5G45340
Transcript Identifier
AT5G45340.1
Gene Type
Coding gene
Location
Chr5 : 18368977-18370909 : negative

Family

Gene family
HOM04M000082
(1007 genes in 29 species)
specific family
Subfamily
ORTHO04M000034
(954 genes in 29 species)
specific family
Duplication type
Block duplicate

Descriptions

Description
cytochrome P450, family 707, subfamily A, polypeptide 3
Curated Summary
Encodes a protein with ABA 8'-hydroxylase activity; involved in ABA catabolism. Mutant analyses show that disruption in the gene results in more drought tolerance whereas overexpression results in increased transpiration rate and reduced drought tolerance. Gene involved in postgermination growth. Plant P450 CYP707A3, ABA 8'-hydroxylase, binds enantioselectively ( )-ABA but not (-)-ABA, whereas the enzyme binds both enantiomers of AHI1 (a structural ABA analogue used as ABA 8'-hydroxylase competitive inhibitor).
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Identifiers

Type Value
full_namecytochrome P450, family 707, subfamily A, polypeptide 3
symbolCYP707A3
tidAT5G45340.1
UniProtQ9FH76

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0055114 IEAGene Ontologyoxidation-reduction process1
GO:0007275 IBAUniProtmulticellular organism development1
GO:0010268 IBAUniProtbrassinosteroid homeostasis1
GO:0016125 IBAUniProtsterol metabolic process1
GO:0016132 IBAUniProtbrassinosteroid biosynthetic process1
GO:0046345 TAS, IEA, UniProtabscisic acid catabolic process1 2
GO:0009414 IMPUniProtresponse to water deprivation1
GO:0009639 IEPUniProtresponse to red or far red light1
GO:0050832 IEAPLAZA Integrative Orthologydefense response to fungusAT4G19230
GO:0048838 IEAPLAZA Integrative Orthologyrelease of seed from dormancyAT4G19230
GO:0009687 IEAPLAZA Integrative Orthologyabscisic acid metabolic processAT4G19230

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005506 IEAUniProtiron ion binding1
GO:0016705 IEAInterProoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 IEAUniProtheme binding1
GO:0019825 ISSGene Ontologyoxygen binding1
GO:0010295 IDAUniProt(+)-abscisic acid 8'-hydroxylase activity1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005576 ISMGene Ontologyextracellular region1
GO:0016021 IEAUniProtintegral component of membrane1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001128Cytochrome P450
IPR002401Cytochrome P450, E-class, group I
IPR017972Cytochrome P450, conserved site

Mapman id Description
11.1.3.2.Phytohormone action.abscisic acid.conjugation and degradation.abscisic acid hydroxylase
No SignalP domains detected for this gene.