Gene: AT5G45110 (Arabidopsis thaliana)

Overview top

Gene Identifier
Transcript Identifier
Gene Type
Coding gene
Chr5 : 18229319-18231334 : positive


Gene family
(109 genes in 27 species)
specific family
Duplication type
Block duplicate


NPR1-like protein 3
Curated Summary
Encodes NPR3, a paralog of NPR1. Involved in negative regulation of defense responses against bacterial and oomycete pathogens. npr3 mutants has elevated level of PR1 expression. Interacts with TGA2, TGA3, TGA5 and TGA6 in yeast two hybrid assays. NPR3 and NPR4 are receptors for the immune signal salicylic acid.
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Type Value







Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0030162 IBAUniProtregulation of proteolysis1
GO:0042787 IBAUniProtprotein ubiquitination involved in ubiquitin-dependent protein catabolic process1
GO:0043161 IBAUniProtproteasome-mediated ubiquitin-dependent protein catabolic process1
GO:2000022 IBAUniProtregulation of jasmonic acid mediated signaling pathway1
GO:0009816 IMPUniProtdefense response to bacterium, incompatible interaction1
GO:0009817 IMPUniProtdefense response to fungus, incompatible interaction1
GO:0009627 IGIUniProtsystemic acquired resistance1
GO:0080185 IGIUniProteffector dependent induction by symbiont of host immune response1
GO:0031348 IEAPLAZA Tree-based Orthologynegative regulation of defense responseAT1G64280
GO:0010112 IEAPLAZA Tree-based Orthologyregulation of systemic acquired resistanceAT1G64280
GO:0010200 IEAPLAZA Tree-based Orthologyresponse to chitinAT4G26120
GO:0050832 IEAPLAZA Integrative Orthologydefense response to fungusAT4G19660
GO:0045893 IEAPLAZA Tree-based Orthologypositive regulation of transcription, DNA-templatedAT1G64280
GO:0001666 IEAPLAZA Tree-based Orthologyresponse to hypoxiaAT1G64280
GO:0008219 IEAPLAZA Tree-based Orthologycell deathAT1G64280
GO:0009408 IEAPLAZA Tree-based Orthologyresponse to heatAT1G64280
GO:0009617 IEAPLAZA Integrative Orthologyresponse to bacteriumAT4G19660
GO:0009625 IEAPLAZA Tree-based Orthologyresponse to insectAT1G64280
GO:0042742 IEAPLAZA Integrative Orthologydefense response to bacteriumAT4G19660
GO:0080027 IEAPLAZA Tree-based Orthologyresponse to herbivoreLOC_Os01g09800
GO:0009862 IEAPLAZA Tree-based Orthologysystemic acquired resistance, salicylic acid mediated signaling pathwayAT1G64280
GO:0009620 IEAPLAZA Integrative Orthologyresponse to fungusAT4G19660
GO:0009611 IEAPLAZA Tree-based Orthologyresponse to woundingAT1G64280
GO:0009682 IEAPLAZA Tree-based Orthologyinduced systemic resistanceAT1G64280
GO:2000031 IEAPLAZA Integrative Orthologyregulation of salicylic acid mediated signaling pathwayAT4G19660

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005515 IPI, IEAGene Ontologyprotein binding1
GO:0031625 IBAUniProtubiquitin protein ligase binding1
GO:1901149 IDAUniProtsalicylic acid binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634 IEAUniProtnucleus1
GO:0005737 IBAUniProtcytoplasm1
GO:0019005 IBAUniProtSCF ubiquitin ligase complex1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR020683Ankyrin repeat-containing domain
IPR024228Regulatory protein NPR, central domain
IPR021094NPR1/NIM1-like, C-terminal
IPR000210BTB/POZ domain
IPR002110Ankyrin repeat
IPR011333SKP1/BTB/POZ domain

Mapman id Description action.salicylic acid.perception and signal transduction.receptor protein (NPR3|4)
No SignalP domains detected for this gene.