Gene: AT5G23630 (Arabidopsis thaliana)

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Gene Identifier
AT5G23630
Transcript Identifier
AT5G23630.1
Gene Type
Coding gene
Location
Chr5 : 7960756-7967644 : negative

Family

Gene family
HOM04M002851
(58 genes in 29 species)
specific family
Subfamily
ORTHO04M005146
(42 genes in 29 species)
specific family

Descriptions

Description
phosphate deficiency response 2
Curated Summary
A member of the eukaryotic type V subfamily (P5) of P-type ATPase cation pumps; MIA is most similar to the human P5 ATPase ATY2(44% identity) and to Spf1p from S. cerevisiae (41% identity). Highly abundant in the endoplasmic reticulum and small vesicles of developing pollen grains and tapetum cells. T-DNA insertional mutants of MIA suffer from imbalances in cation homeostasis and exhibit a severe reduction in fertility. Mutant microspores fail to separate from tetrads and pollen grains are fragile with an abnormal morphology and altered cell wall structure. MIA is also named PDR2 and was shown to be required for proper expression of SCARECROW (SCR), a key regulator of root patterning, and for stem-cell maintenance in Pi-deprived roots.
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Identifiers

Type Value
AliasMIA,MALE GAMETOGENESIS IMPAIRED ANTHERS
symbolPDR2
tidAT5G23630.1
UniProtQ9LT02

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006812 IEAInterProcation transport
GO:0006874 IBAUniProtcellular calcium ion homeostasis1
GO:0006875 IMPUniProtcellular metal ion homeostasis1
GO:0009846 IMPUniProtpollen germination1
GO:0010152 IMPUniProtpollen maturation1
GO:0010073 IMPUniProtmeristem maintenance1
GO:0016036 IMPUniProtcellular response to phosphate starvation1
GO:0048867 IMPUniProtstem cell fate determination1
GO:0006810 IEA, IMP, UniProttransport
GO:0006855 ISSUniProtdrug transmembrane transport

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0000166 IEAInterPronucleotide binding
GO:0016887 IEAUniProtATPase activity
GO:0005388 IBAUniProtcalcium-transporting ATPase activity1
GO:0005524 IEAUniProtATP binding1
GO:0019829 IGI, ISSGene Ontologycation-transporting ATPase activity1 2
GO:0046872 IEAUniProtmetal ion binding1
GO:0042626 IBAUniProtATPase activity, coupled to transmembrane movement of substances

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0016021 IBA, IEA, UniProtintegral component of membrane
GO:0005789 IEAUniProtendoplasmic reticulum membrane1
GO:0005887 IBAUniProtintegral component of plasma membrane1
GO:0005783 IDAUniProtendoplasmic reticulum1
GO:0005886 IBA, IDA, UniProtplasma membrane1

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR023299P-type ATPase, cytoplasmic domain N
IPR018303P-type ATPase, phosphorylation site
IPR023214HAD-like domain
IPR023298P-type ATPase, transmembrane domain
IPR008250P-type ATPase, A domain
IPR001757P-type ATPase
IPR006544P-type ATPase, subfamily V

Mapman id Description
24.1.2.5.1.Solute transport.primary active transport.P-type ATPase superfamily.P5 family.P5-type cation-transporting ATPase (MIA)
No SignalP domains detected for this gene.