Gene: AT4G39640 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT4G39640
Transcript Identifier
AT4G39640.1
Gene Type
Coding gene
Location
Chr4 : 18400608-18402861 : positive

Family

Gene family
HOM04M001548
(96 genes in 29 species)
specific family
Subfamily
ORTHO04M002203
(75 genes in 29 species)
specific family
Duplication type
Tandem duplicate

Descriptions

Description
gamma-glutamyl transpeptidase 1
Curated Summary
The gene encodes a gamma-glutamyltransferase (AKA gamma-glutamyl transpeptidase, EC 2.3.2.2) that is located in vascular tissues (predominantly phloem) of leaves and is involved in the degradation of glutathione. The encoded enzyme also mitigates oxidative stress by metabolizing GSSG (oxidized form of GSH - glutathione) in the apoplast.
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Identifiers

Type Value
symbolGGT1
tidAT4G39640.1
UniProtQ8VYW6

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006751 IDA, IEA, UniProtglutathione catabolic process1
GO:0006979 IDAUniProtresponse to oxidative stress1
GO:0006545 IEAUniProtglycine biosynthetic process
GO:0042853 IEAUniProtL-alanine catabolic process
GO:0009853 TASUniProtphotorespiration
GO:0001666 IEPUniProtresponse to hypoxia
GO:0034775 IEAPLAZA Integrative Orthologyglutathione transmembrane transportAT4G39650
GO:0006805 IEAPLAZA Integrative Orthologyxenobiotic metabolic processAT1G69820

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0036374 IEAUniProtglutathione hydrolase activity1
GO:0016756 IDAUniProtglutathione gamma-glutamylcysteinyltransferase activity1
GO:0008453 IDAUniProtalanine-glyoxylate transaminase activity
GO:0047958 IDAUniProtglycine:2-oxoglutarate aminotransferase activity
GO:0004021 IDAUniProtL-alanine:2-oxoglutarate aminotransferase activity
GO:0030170 IEAUniProtpyridoxal phosphate binding

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0048046 IDAUniProtapoplast1
GO:0009507 IDAUniProtchloroplast
GO:0016020 IDAUniProtmembrane
GO:0005777 IDAUniProtperoxisome
GO:0005773 IDAUniProtvacuole
GO:0009505 IDAUniProtplant-type cell wall
GO:0009506 IDAUniProtplasmodesma
GO:0005886 IEAPLAZA Integrative Orthologyplasma membraneAT4G39650
GO:0009570 IEAPLAZA Integrative Orthologychloroplast stromaAT4G39650

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000101Gamma-glutamyltranspeptidase
IPR029055Nucleophile aminohydrolases, N-terminal

Mapman id Description
19.4.4.1.Protein homeostasis.proteolysis.threonine-type peptidase activities.T3-class gamma-glutamyl transpeptidase (GGT)
No SignalP domains detected for this gene.