Gene: AT4G34890 (Arabidopsis thaliana)

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Gene Identifier
AT4G34890
Transcript Identifier
AT4G34890.1
Gene Type
Coding gene
Location
Chr4 : 16618736-16624983 : negative

Family

Gene family
HOM04M000557
(220 genes in 29 species)
specific family
Subfamily
ORTHO04M005330
(41 genes in 29 species)
specific family
Duplication type
Tandem duplicate

Descriptions

Description
xanthine dehydrogenase 1
Curated Summary
Encodes a xanthine dehydrogenase, involved in purine catabolism. Ubiquitously expressed, but the transcript level is altered during aging, senescence, salt and cold stress, ABA treatment, and dark treatment. RNAi lines that suppress both XDH1 and XDH2 produce small plants with reduced fertility and accelerated leaf senescence. Role in drought tolerance.
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Identifiers

Type Value
AliasATXDH1,XANTHINE DEHYDROGENASE 1
symbolXDH1
tidAT4G34890.1
UniProtQ8GUQ8

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0055114 IEAGene Ontologyoxidation-reduction process1
GO:0009115 IBAUniProtxanthine catabolic process1
GO:0006145 IMP, TAS, UniProtpurine nucleobase catabolic process1 2
GO:0042554 IMPUniProtsuperoxide anion generation1
GO:0046110 IMPUniProtxanthine metabolic process1
GO:0000302 IMPUniProtresponse to reactive oxygen species1
GO:0009414 IMPUniProtresponse to water deprivation1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0003824 IEAInterProcatalytic activity
GO:0050660 IBA, IEA, UniProtflavin adenine dinucleotide binding1
GO:0016491 IEAInterProoxidoreductase activity
GO:0046872 IEAInterPrometal ion binding
GO:0009055 IEAUniProtelectron carrier activity1
GO:0051536 IEAInterProiron-sulfur cluster binding
GO:0005506 IEAUniProtiron ion binding1
GO:0051537 IEAUniProt2 iron, 2 sulfur cluster binding1
GO:0016614 IEAUniProtoxidoreductase activity, acting on CH-OH group of donors1
GO:0004854 IDA, ISS, UniProtxanthine dehydrogenase activity1 2
GO:0016903 IBAUniProtoxidoreductase activity, acting on the aldehyde or oxo group of donors1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005829 IDAUniProtcytosol1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000674Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead
IPR016167FAD-binding, type 2, subdomain 1
IPR016169CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2
IPR012675Beta-grasp domain
IPR002888[2Fe-2S]-binding
IPR008274Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding
IPR005107CO dehydrogenase flavoprotein, C-terminal
IPR0010412Fe-2S ferredoxin-type iron-sulfur binding domain
IPR002346Molybdopterin dehydrogenase, FAD-binding
IPR016208Aldehyde oxidase/xanthine dehydrogenase
IPR0060582Fe-2S ferredoxin, iron-sulphur binding site
IPR016166FAD-binding, type 2

Mapman id Description
6.1.4.5.Nucleotide metabolism.purines.catabolism.xanthine dehydrogenase
10.1.2.Redox homeostasis.reactive oxygen generation.xanthine dehydrogenase
No SignalP domains detected for this gene.