Gene: AT4G34060 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT4G34060
Transcript Identifier
AT4G34060.3
Gene Type
Coding gene
Location
Chr4 : 16313411-16319254 : positive

Family

Gene family
HOM04M000985
(140 genes in 29 species)
specific family

Descriptions

Description
demeter-like protein 3
Curated Summary
Encodes a protein with 5-meC and thymine-DNA glycosylase activity with a preference for CpG and CpHpG sequences. Involved in maintaining methylation marks.
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Identifiers

Type Value
symbolDML3
tidAT4G34060.3

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006284 IEAUniProtbase-excision repair1
GO:0006281 IEAInterProDNA repair
GO:0006351 IEAUniProttranscription, DNA-templated1
GO:0006355 IEAUniProtregulation of transcription, DNA-templated1
GO:0010216 IMPUniProtmaintenance of DNA methylation1
GO:0006342 IEAPLAZA Integrative Orthologychromatin silencingAT2G36490
GO:0050832 IEAPLAZA Integrative Orthologydefense response to fungusAT2G36490
GO:0080111 IEAPLAZA Integrative OrthologyDNA demethylationAT2G36490
GO:0031936 IEAPLAZA Integrative Orthologynegative regulation of chromatin silencingAT2G36490
GO:0006306 IEAPLAZA Integrative OrthologyDNA methylationAT2G36490

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0051539 IEAUniProt4 iron, 4 sulfur cluster binding1
GO:0003824 IEAUniProtcatalytic activity1
GO:0003677 IEAUniProtDNA binding1
GO:0046872 IEAUniProtmetal ion binding1
GO:0019104 IDAUniProtDNA N-glycosylase activity1
GO:0003906 IEAPLAZA Integrative OrthologyDNA-(apurinic or apyrimidinic site) lyase activityAT2G36490
GO:0005515 IEAPLAZA Integrative Orthologyprotein bindingAT2G36490

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634 IEA, ISM, UniProtnucleus1 2

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR023170Helix-turn-helix, base-excision DNA repair, C-terminal
IPR028924Permuted single zf-CXXC unit
IPR028925Demeter, RRM-fold domain
IPR003651Endonuclease III-like, iron-sulphur cluster loop motif
IPR003265HhH-GPD domain
IPR011257DNA glycosylase

Mapman id Description
12.5.3.1.Chromatin organisation.DNA methylation.ROS1-mediated DNA demethylation.methylcytosine-specific DNA glycosylase (ROS1)
No SignalP domains detected for this gene.