Gene: AT4G29210 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT4G29210
Transcript Identifier
AT4G29210.2
Gene Type
Coding gene
Location
Chr4 : 14400990-14402752 : positive

Family

Gene family
HOM04M001548
(96 genes in 29 species)
specific family
Subfamily
ORTHO04M002203
(75 genes in 29 species)
specific family

Descriptions

Description
gamma-glutamyl transpeptidase 4
Curated Summary
The gene encodes a gamma-glutamyltransferase (AKA gamma-glutamyl transpeptidase, EC 2.3.2.2) that is located in the vacuole and is most active in roots. The encoded enzyme is involved in the initial degradation of glutathione conjugates in this cell compartment. It is also induced by xenobiotics and contributes to xenobiotics metabolism. Note that conflicting nomenclature exists in the literature: At4g29210 is named as GGT3 in Plant J. 2007 Mar 49(5):878-88; At4g29210 is named as GGT4 and At1g69820 as GGT3 in Plant Physiol. 2007 Aug 144(4):1715-32.
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Identifiers

Type Value
AliasGGT3,gamma-glutamyl transpeptidase 3
symbolGGT4
tidAT4G29210.2
UniProtQ9M0G0-2

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006751 IDA, IEA, UniProtglutathione catabolic process1
GO:0009636 IEAUniProtresponse to toxic substance1
GO:0006805 IEPUniProtxenobiotic metabolic process1
GO:0006508 IMPGene Ontologyproteolysis1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0036374 IEA, IMPUniProtglutathione hydrolase activity1
GO:0016756 IDAUniProtglutathione gamma-glutamylcysteinyltransferase activity1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005774 IEAUniProtvacuolar membrane1
GO:0016021 IEAUniProtintegral component of membrane1
GO:0005773 IDAUniProtvacuole1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000101Gamma-glutamyltranspeptidase
IPR029055Nucleophile aminohydrolases, N-terminal

Mapman id Description
19.4.4.1.Protein homeostasis.proteolysis.threonine-type peptidase activities.T3-class gamma-glutamyl transpeptidase (GGT)
No SignalP domains detected for this gene.