PLAZA 4.0 Monocots gene overview : AT4G29170

Gene: AT4G29170 (Arabidopsis thaliana)

Curated Summary: A homolog of yeast, mouse and human mnd1delta protein. Null mutants exhibit normal vegetative and flower development; however, during prophase I, chromosomes become fragmented resulting in random distribution of the fragments between polyads. Both male and female meiosis are defective and strong accumulation of AtRAD51 was observed in the inflorescence nuclei of mutant plants. Similarly to its yeast and animal homologues, AtMnd1 might play a role in DSB repair during meiosis.

GO term	Evidence(s)	Provider	Description	Source
GO:0007131	IBA	Gene Ontology	reciprocal meiotic recombination	1
GO:0006302	IMP	Gene Ontology	double-strand break repair	1
GO:0009553	IMP	Gene Ontology	embryo sac development	1
GO:0009555	IMP	Gene Ontology	pollen development	1
GO:0010212	IMP	Gene Ontology	response to ionizing radiation	1

GO term	Evidence(s)	Provider	Description	Source
GO:0003690	IBA	Gene Ontology	double-stranded DNA binding	1
GO:0005515	IPI	Gene Ontology	protein binding	1

GO term	Evidence(s)	Provider	Description	Source
GO:0005634	IBA, ISM	Gene Ontology	nucleus	1 2
GO:0005730	IEA	Gene Ontology	nucleolus	1

Experimental Evidence

Electronic Evidence

Computational Reviewed Evidence

InterPro	Description
IPR011991	Winged helix-turn-helix DNA-binding domain
IPR005647	Meiotic nuclear division protein 1

Mapman id	Description
13.3.6.4.5.1	.Cell cycle organisation.mitosis and meiosis.meiotic recombination.DNA strand exchange.HOP2-MND1 presynaptic filament stabilization complex.component MND1

No SignalP domains detected for this gene.