Gene: AT4G24220 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT4G24220
Transcript Identifier
AT4G24220.1
Gene Type
Coding gene
Location
Chr4 : 12565219-12566474 : positive

Family

Gene family
HOM04M001403
(105 genes in 27 species)
specific family
Subfamily
ORTHO04M001791
(85 genes in 27 species)
specific family

Descriptions

Description
NAD(P)-binding Rossmann-fold superfamily protein
Curated Summary
encodes a progesterone-5beta-reductase-like protein. It has enone reductase activity against a wide range of substrates, including 3-oxo-Δ-4,5-steroids in vitro. The in vivo substrates and product of this enzyme have not yet been elucidated but it is likely to participate in steroid metabolism. The protein contains a mammalian death domain involved in programmed cell death. The gene is expressed in the vascular system and mutants carrying a dominant mutation in the gene have defective vascular patterning. VEP1 gene expression is induced specifically by wounding.
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Identifiers

Type Value
Alias5[beta]-StR,Δ4,5-steroid-5[beta]-reductase,AWI31
full_nameVEIN PATTERNING 1
symbolVEP1
tidAT4G24220.1
UniProtQ9STX2

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0055114 IEAGene Ontologyoxidation-reduction process1
GO:0009611 IEPUniProtresponse to wounding1
GO:0010051 IMPUniProtxylem and phloem pattern formation1
GO:0008202 IDAUniProtsteroid metabolic process1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0047787 IEAUniProtdelta4-3-oxosteroid 5beta-reductase activity1
GO:0035671 IDAUniProtenone reductase activity1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005829 IDAUniProtcytosol1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR016040NAD(P)-binding domain

Mapman id Description
35.1not assigned.annotated
No SignalP domains detected for this gene.