Gene: AT4G19690 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT4G19690
Transcript Identifier
AT4G19690.2
Gene Type
Coding gene
Location
Chr4 : 10707487-10708723 : positive

Family

Gene family
HOM04M000320
(334 genes in 28 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

Description
iron-regulated transporter 1
Curated Summary
The gene encodes Fe2 transporter protein. It is a member of the Zrt/Irt-like protein (ZIP) family of transporters. AtIRT1 has broad specificity for divalent heavy metals, mediating the transport of zinc, manganese, cobalt and cadmium under Fe-deficient conditions. IRT1 is monoubiquitinated to promote endocytic trafficking.
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Identifiers

Type Value
AliasATIRT1,ARABIDOPSIS IRON-REGULATED TRANSPORTER 1
symbolIRT1
tidAT4G19690.2
UniProtQ38856

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0030001 IMP, IEA, UniProtmetal ion transport1
GO:0055085 IEAInterProtransmembrane transport
GO:0071577 IEAGene Ontologyzinc II ion transmembrane transport1
GO:0055072 IEAUniProtiron ion homeostasis1
GO:0006826 TASGene Ontologyiron ion transport1
GO:0006828 TASGene Ontologymanganese ion transport1
GO:0006829 TASGene Ontologyzinc II ion transport1
GO:0015691 TASGene Ontologycadmium ion transport1
GO:0006879 IMPGene Ontologycellular iron ion homeostasis1
GO:0009617 IEPUniProtresponse to bacterium1
GO:0071281 IEPUniProtcellular response to iron ion1
GO:0071369 IEPUniProtcellular response to ethylene stimulus1
GO:0071732 IEPUniProtcellular response to nitric oxide1
GO:0015675 IMPUniProtnickel cation transport1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0046873 IEAInterPrometal ion transmembrane transporter activity
GO:0005385 IEA, TAS, UniProtzinc ion transmembrane transporter activity1 2
GO:0005381 TAS, IGI, UniProtiron ion transmembrane transporter activity1 2
GO:0005384 TASGene Ontologymanganese ion transmembrane transporter activity1
GO:0015086 TASGene Ontologycadmium ion transmembrane transporter activity1
GO:0015088 IGIUniProtcopper uptake transmembrane transporter activity1
GO:0005515 IEAPLAZA Integrative Orthologyprotein bindingAT1G31260

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0016020 IEAInterPromembrane
GO:0016021 IEAUniProtintegral component of membrane1
GO:0005769 IEAUniProtearly endosome1
GO:0005773 IEAUniProtvacuole1
GO:0005886 IDA, ISM, UniProtplasma membrane1 2
GO:0005802 IDAUniProttrans-Golgi network1
GO:0005768 IDAUniProtendosome1 2

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003689Zinc/iron permease
IPR004698Zinc/iron permease, fungal/plant

Mapman id Description
24.2.11.1.Solute transport.carrier-mediated transport.ZIP family.metal cation transporter (ZIP)
25.4.2.2.Nutrient uptake.iron uptake.reduction-based strategy uptake.ferrous cation uptake transporter (IRT)
No SignalP domains detected for this gene.