Gene: AT4G17380 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT4G17380
Transcript Identifier
AT4G17380.1
Gene Type
Coding gene
Location
Chr4 : 9708742-9714068 : positive

Family

Gene family
HOM04M000657
(193 genes in 29 species)
specific family
Duplication type
Tandem duplicate

Descriptions

Description
MUTS-like protein 4
Curated Summary
Encodes the Arabidopsis homolog of MSH4, a meiosis-specific member of the MutS-homolog family of genes. It is expressed only in floral tissues and only during early meiotic prophase I, preceding the synapsis of homologous chromosomes. It is involved in the early steps of recombination.
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Identifiers

Type Value
AliasATMSH4,ARABIDOPSIS MUTS HOMOLOG 4
symbolMSH4
tidAT4G17380.1
UniProtF4JP48

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006298 IBA, IEA, ISS, UniProtmismatch repair1
GO:0007129 IMPUniProtsynapsis1
GO:0051026 IBAUniProtchiasma assembly
GO:0045143 IMPUniProthomologous chromosome segregation
GO:0010777 IMPUniProtmeiotic mismatch repair involved in reciprocal meiotic recombination

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005524 IEA, ISS, UniProtATP binding1
GO:0030983 IBA, IEA, UniProtmismatched DNA binding
GO:0003684 ISSGene Ontologydamaged DNA binding1
GO:0008094 IBAUniProtDNA-dependent ATPase activity

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634 ISMGene Ontologynucleus1
GO:0000794 IDAUniProtcondensed nuclear chromosome1
GO:0009506 IDAUniProtplasmodesma1
GO:0043073 IDAUniProtgerm cell nucleus
GO:0000795 IBAUniProtsynaptonemal complex

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR007860DNA mismatch repair protein MutS, connector domain
IPR007696DNA mismatch repair protein MutS, core
IPR000432DNA mismatch repair protein MutS, C-terminal
IPR007861DNA mismatch repair protein MutS, clamp
IPR011184DNA mismatch repair MutS
IPR027417P-loop containing nucleoside triphosphate hydrolase

Mapman id Description
13.3.6.5.1.2.1.Cell cycle organisation.mitosis and meiosis.meiotic recombination.meiotic crossover.class I interference-sensitive crossover pathway.MSH4-MSH5 Holliday junction stabilizing heterodimer.component MSH4
No SignalP domains detected for this gene.