PLAZA 4.0 Monocots gene overview : AT4G16740

Gene: AT4G16740 (Arabidopsis thaliana)

Curated Summary: Encodes an (E,E)-alpha-farnesene synthase in the Col ecotype of Arabidopsis. This enzyme can also catalyze the formation of (E)-beta-ocimene as well as trace amounts of myrcene and other related compounds in vitro. The cytosolic localization of the protein may make it favor (E,E)-alpha-farnesene biosynthesis because the precursor of this product, FPP, is primarily cytosolic. Transcript levels for this gene increase in response to treatment with the jasmonic acid mimic coronalon or in response to the insect Plutella xylostella. TPS03 transcripts can also be detected in flowers. A similar protein from the C24 ecotype with one amino acid change (S267F) has a different substrate specificity.

GO term	Evidence(s)	Provider	Description	Source
GO:0008152	IEA, ISS	UniProt	metabolic process
GO:0080027	IEP	UniProt	response to herbivore	1
GO:0009611	IEP	UniProt	response to wounding	1
GO:0009753	IEP	UniProt	response to jasmonic acid	1
GO:0009625	IEP	UniProt	response to insect	1
GO:0016106	IMP	UniProt	sesquiterpenoid biosynthetic process	1
GO:0050832	IEA	PLAZA Integrative Orthology	defense response to fungus	AT3G25830
GO:0016099	IEA	PLAZA Integrative Orthology	monoterpenoid biosynthetic process	AT2G24210
GO:0043693	IEA	PLAZA Integrative Orthology	monoterpene biosynthetic process	AT3G25810
GO:0051762	IEA	PLAZA Tree-based Orthology	sesquiterpene biosynthetic process	AT5G44630
GO:0048364	IEA	PLAZA Integrative Orthology	root development	AT3G25830
GO:0045338	IEA	PLAZA Tree-based Orthology	farnesyl diphosphate metabolic process	AT4G13300
GO:0009735	IEA	PLAZA Tree-based Orthology	response to cytokinin	Solyc09g092470.2

GO term	Evidence(s)	Provider	Description	Source
GO:0010333	IEA, ISS	UniProt	terpene synthase activity
GO:0016829	IEA	InterPro	lyase activity
GO:0000287	IEA	UniProt	magnesium ion binding	1
GO:0102701	IEA	UniProt	tricyclene synthase activity	1
GO:0034768	IDA	UniProt	(E)-beta-ocimene synthase activity	1
GO:0050551	IDA	UniProt	myrcene synthase activity	1
GO:0052578	IMP	UniProt	alpha-farnesene synthase activity	1
GO:0034007	IEA	PLAZA Tree-based Orthology	S-linalool synthase activity	AT1G61680
GO:0010334	IEA	PLAZA Integrative Orthology	sesquiterpene synthase activity	AT3G25810
GO:0050550	IEA	PLAZA Integrative Orthology	pinene synthase activity	AT3G25810
GO:0005515	IEA	PLAZA Integrative Orthology	protein binding	AT3G25810
GO:0050552	IEA	PLAZA Integrative Orthology	(4S)-limonene synthase activity	AT3G25810
GO:0009975	IEA	PLAZA Tree-based Orthology	cyclase activity	AT4G13300
GO:0004795	IEA	PLAZA Tree-based Orthology	threonine synthase activity	AT4G15870
GO:0080017	IEA	PLAZA Tree-based Orthology	alpha-humulene synthase activity	AT5G23960
GO:0080016	IEA	PLAZA Tree-based Orthology	(-)-E-beta-caryophyllene synthase activity	AT5G23960
GO:0080015	IEA	PLAZA Integrative Orthology	sabinene synthase activity	AT3G25810
GO:0034002	IEA	PLAZA Integrative Orthology	(R)-limonene synthase activity	AT3G25810

GO term	Evidence(s)	Provider	Description	Source
GO:0009507	ISM	Gene Ontology	chloroplast	1
GO:0005829	IDA	UniProt	cytosol	1
GO:0016021	IEA	UniProt	integral component of membrane
GO:0009570	ISS	UniProt	chloroplast stroma
GO:0016020	IEA	PLAZA Tree-based Orthology	membrane	AT1G31950
GO:0009506	IEA	PLAZA Tree-based Orthology	plasmodesma	AT5G44630
GO:0005777	IEA	PLAZA Tree-based Orthology	peroxisome	AT4G13280

Experimental Evidence

Electronic Evidence

Computational Reviewed Evidence

InterPro	Description
IPR001906	Terpene synthase, N-terminal domain
IPR008949	Isoprenoid synthase domain
IPR005630	Terpene synthase, metal-binding domain
IPR008930	Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid

Mapman id	Description
9.1.4.2	.Secondary metabolism.terpenoids.terpene biosynthesis.mono-/sesquiterpene-/diterpene synthase

No SignalP domains detected for this gene.