Gene: AT4G14220 (Arabidopsis thaliana)

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Gene Identifier
AT4G14220
Transcript Identifier
AT4G14220.1
Gene Type
Coding gene
Location
Chr4 : 8196012-8198240 : positive

Family

Gene family
HOM04M001812
(84 genes in 27 species)
specific family
Subfamily
ORTHO04M001982
(80 genes in 27 species)
specific family

Descriptions

Description
RING-H2 group F1A
Curated Summary
encodes a RING-type E3 ubiquitin ligase implicated in gametogenesis. RHF1a can interact with the cell cycle inhibitor ICK4/KRP6 in vitro. It apppears to target ICK4KRP6 for degradation following meiosis in order to allow the mitoses associated with megagametogenesis and microgametogenesis to occur. RHF1a is expressed in the carpels throughout floral development. It is expressed in various tissues of the anthers during the early stages of anther development but not in stage 12 flowers and beyond.
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Identifiers

Type Value
symbolRHF1A
tidAT4G14220.1
UniProtQ4TU14

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0000209 IBAUniProtprotein polyubiquitination1
GO:0042787 IBAUniProtprotein ubiquitination involved in ubiquitin-dependent protein catabolic process1
GO:0043161 IBAUniProtproteasome-mediated ubiquitin-dependent protein catabolic process1
GO:0009561 IGIUniProtmegagametogenesis1
GO:0010498 IDAUniProtproteasomal protein catabolic process1
GO:0016567 IDAUniProtprotein ubiquitination1
GO:0051726 IGIUniProtregulation of cell cycle1
GO:0055046 IGIUniProtmicrogametogenesis1
GO:0051603 IEAPLAZA Tree-based Orthologyproteolysis involved in cellular protein catabolic processAT5G22000

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0008270 IEA, ISSGene Ontologyzinc ion binding1 2
GO:0061630 IBAUniProtubiquitin protein ligase activity1
GO:0004842 IDAUniProtubiquitin-protein transferase activity1
GO:0005515 IPIGene Ontologyprotein binding1
GO:0046872 IEAUniProtmetal ion binding

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634 ISMGene Ontologynucleus1
GO:0016020 IDAUniProtmembrane1
GO:0005886 IEAPLAZA Tree-based Orthologyplasma membraneAT5G22000

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001841Zinc finger, RING-type
IPR013083Zinc finger, RING/FYVE/PHD-type

Mapman id Description
35.1not assigned.annotated
No SignalP domains detected for this gene.