Gene: AT4G02570 (Arabidopsis thaliana)

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Gene Identifier
AT4G02570
Transcript Identifier
AT4G02570.4
Gene Type
Coding gene
Location
Chr4 : 1129315-1133435 : positive

Family

Gene family
HOM04M000392
(290 genes in 29 species)
specific family
Subfamily
ORTHO04M001263
(104 genes in 29 species)
specific family
Duplication type
Block duplicate

Descriptions

Description
cullin 1
Curated Summary
Encodes a cullin that is a component of SCF ubiquitin ligase complexes involved in mediating responses to auxin and jasmonic acid. Homozygous auxin-resistant mutants arrest growth soon after germination, lacking a root and hypocotyl. Heterozygotes display a variety of phenotypes consistent with impaired auxin response.
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Identifiers

Type Value
AliasATCUL1,cullin 1,AXR6,AUXIN RESISTANT 6
symbolCUL1
tidAT4G02570.4
UniProtQ94AH6

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006511 IEAInterProubiquitin-dependent protein catabolic process
GO:0007049 IEAUniProtcell cycle1
GO:0009734 IEAUniProtauxin-activated signaling pathway1
GO:0009873 IEAUniProtethylene-activated signaling pathway1
GO:0042787 IBAUniProtprotein ubiquitination involved in ubiquitin-dependent protein catabolic process1
GO:0009733 IMPUniProtresponse to auxin1
GO:0009793 IMPUniProtembryo development ending in seed dormancy1
GO:0009753 IMPUniProtresponse to jasmonic acid1
GO:0009867 TASUniProtjasmonic acid mediated signaling pathway1
GO:0010265 IPIGene OntologySCF complex assembly1
GO:0042752 IMPUniProtregulation of circadian rhythm1
GO:0010087 IMPUniProtphloem or xylem histogenesis1
GO:0048366 IMPUniProtleaf development1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0031625 IBA, IEA, UniProtubiquitin protein ligase binding1
GO:0061630 IBAGene Ontologyubiquitin protein ligase activity1
GO:0005515 IPIGene Ontologyprotein binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0031461 IBA, IEA, UniProtcullin-RING ubiquitin ligase complex1
GO:0005634 IDA, ISM, UniProtnucleus1 2
GO:0000151 IPIGene Ontologyubiquitin ligase complex1
GO:0005819 IDAUniProtspindle1
GO:0009524 IDAUniProtphragmoplast1
GO:0000794 IDAUniProtcondensed nuclear chromosome1
GO:0005737 IDAUniProtcytoplasm1
GO:0005829 IDAUniProtcytosol1
GO:0009941 IEAPLAZA Integrative Orthologychloroplast envelopeAT1G02980

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR011991Winged helix-turn-helix DNA-binding domain
IPR001373Cullin, N-terminal
IPR019559Cullin protein, neddylation domain
IPR016157Cullin, conserved site
IPR016158Cullin homology
IPR016159Cullin repeat-like-containing domain

Mapman id Description
19.2.2.8.1.2.Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.SKP1-CUL1-FBX (SCF) E3 ligase complexes.scaffold component CUL1/CUL2
No SignalP domains detected for this gene.