Gene: AT4G02060 (Arabidopsis thaliana)

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Gene Identifier
AT4G02060
Transcript Identifier
AT4G02060.2
Gene Type
Coding gene
Location
Chr4 : 901484-905297 : positive

Family

Gene family
HOM04M000333
(325 genes in 29 species)
specific family
Subfamily
ORTHO04M007178
(34 genes in 29 species)
specific family

Descriptions

Description
Minichromosome maintenance (MCM2/3/5) family protein
Curated Summary
Member of the minichromosome maintenance complex, involved in DNA replication initiation. Abundant in proliferating and endocycling tissues. Localized in the nucleus during G1, S and G2 phases of the cell cycle, and are released into the cytoplasmic compartment during mitosis. Binds chromatin.
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Identifiers

Type Value
AliasMCM7
full_namePROLIFERA
symbolPRL
tidAT4G02060.2
UniProtP43299

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006270 IEA, ISS, UniProtDNA replication initiation1 2
GO:0006260 IEAInterProDNA replication
GO:0006351 IEAUniProttranscription, DNA-templated1
GO:0006355 IEAUniProtregulation of transcription, DNA-templated1
GO:0007049 IEAUniProtcell cycle1
GO:0010182 TASUniProtsugar mediated signaling pathway1
GO:0006268 TASUniProtDNA unwinding involved in DNA replication1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0003677 IEA, ISS, UniProtDNA binding1 2
GO:0003678 IEAUniProtDNA helicase activity1
GO:0005524 IEA, ISS, UniProtATP binding1 2
GO:0008094 ISSGene OntologyDNA-dependent ATPase activity1
GO:0046872 IEAUniProtmetal ion binding1
GO:0005515 IPIGene Ontologyprotein binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634 IDA, ISM, IEA, UniProtnucleus1 2
GO:0042555 IEAUniProtMCM complex1
GO:0000347 IDAUniProtTHO complex1
GO:0005737 IDAUniProtcytoplasm1
GO:0005829 RCAGene Ontologycytosol1

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR008050DNA replication licensing factor Mcm7
IPR033762MCM OB domain
IPR001208MCM domain
IPR027925MCM N-terminal domain
IPR018525Mini-chromosome maintenance, conserved site
IPR031327Mini-chromosome maintenance protein
IPR003593AAA+ ATPase domain
IPR027417P-loop containing nucleoside triphosphate hydrolase
IPR012340Nucleic acid-binding, OB-fold

Mapman id Description
13.2.1.2.6.Cell cycle organisation.DNA replication.preinitiation.MCM replicative DNA helicase complex.component MCM7
No SignalP domains detected for this gene.