Gene: AT3G44310 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT3G44310
Transcript Identifier
AT3G44310.1
Gene Type
Coding gene
Location
Chr3 : 15986901-15988841 : positive

Family

Gene family
HOM04M002023
(77 genes in 27 species)
specific family
Subfamily
ORTHO04M002509
(69 genes in 27 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

Description
nitrilase 1
Curated Summary
Mutants are resistant to indole-3-acetonitrile (IAN). NIT1 catalyzes the terminal activation step in indole-acetic acid biosynthesis. Predominantly expressed isoform of nitrilase isoenzyme family. Aggregation of NIT1 in cells directly abutting wound sites is one of the earliest events associated with wound and herbicide-induced cell death. The protein undergoes thiolation following treatment with the oxidant tert-butylhydroperoxide. It is also involved in the conversion of IAN to IAM (indole-3-acetamide) and other non-auxin-related metabolic processes.
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Identifiers

Type Value
AliasATNIT1,A. THALIANA NITRILASE 1,NITI
symbolNIT1
tidAT3G44310.1
UniProtP32961

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006807 IEAUniProtnitrogen compound metabolic process1
GO:0009684 TASUniProtindoleacetic acid biosynthetic process1
GO:0009617 IEAPLAZA Integrative Orthologyresponse to bacteriumAT3G44300
GO:0051410 IEAPLAZA Tree-based Orthologydetoxification of nitrogen compoundAT5G22300
GO:0009970 IEAPLAZA Integrative Orthologycellular response to sulfate starvationAT3G44320
GO:0019762 IEAPLAZA Integrative Orthologyglucosinolate catabolic processAT3G44320
GO:0046686 IEAPLAZA Integrative Orthologyresponse to cadmium ionAT3G44300
GO:0019499 IEAPLAZA Tree-based Orthologycyanide metabolic processAT5G22300

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0016810 IEAUniProthydrolase activity, acting on carbon-nitrogen (but not peptide) bonds1
GO:0000257 IDAUniProtnitrilase activity1
GO:0080109 IDAUniProtindole-3-acetonitrile nitrile hydratase activity1
GO:0080061 IDAUniProtindole-3-acetonitrile nitrilase activity1
GO:0047558 IEAPLAZA Tree-based Orthology3-cyanoalanine hydratase activityAT5G22300
GO:0018822 IEAPLAZA Tree-based Orthologynitrile hydratase activityAT5G22300
GO:0047427 IEAPLAZA Tree-based Orthologycyanoalanine nitrilase activityAT5G22300

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005886 IDA, ISM, UniProtplasma membrane1 2
GO:0009507 IDAUniProtchloroplast1
GO:0048046 IDAUniProtapoplast1
GO:0005829 IDAUniProtcytosol1
GO:0009506 IDAUniProtplasmodesma1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003010Carbon-nitrogen hydrolase
IPR000132Nitrilase/cyanide hydratase, conserved site

Mapman id Description
9.5.2.5.Secondary metabolism.glucosinolates.glucosinolate degradation.nitrilase
No SignalP domains detected for this gene.