Gene: AT3G44300 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT3G44300
Transcript Identifier
AT3G44300.1
Gene Type
Coding gene
Location
Chr3 : 15983351-15985172 : positive

Family

Gene family
HOM04M002023
(77 genes in 27 species)
specific family
Subfamily
ORTHO04M002509
(69 genes in 27 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

Description
nitrilase 2
Curated Summary
Encodes an enzyme that catalyzes the hydrolysis of indole-3-acetonitrile (IAN) to indole-3-acetic acid (IAA) (nitrile aminohydrolase, EC 3.5.5.1) and IAN to indole-3-acetamide (IAM) at lower levels. Mutants have reduced sensitivity to IAN and are sensitive to IAA. This enzyme likely participates in other non-auxin-related metabolic pathways.
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Identifiers

Type Value
AliasAtNIT2,nitrilase 2
symbolNIT2
tidAT3G44300.1
UniProtP32962

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006807 IEAInterPronitrogen compound metabolic process
GO:0009617 IEPGene Ontologyresponse to bacterium1
GO:0046686 IEPUniProtresponse to cadmium ion1
GO:0009684 TASUniProtindoleacetic acid biosynthetic process1
GO:0051410 IEAPLAZA Tree-based Orthologydetoxification of nitrogen compoundAT5G22300
GO:0009970 IEAPLAZA Integrative Orthologycellular response to sulfate starvationAT3G44320
GO:0019762 IEAPLAZA Integrative Orthologyglucosinolate catabolic processAT3G44320
GO:0019499 IEAPLAZA Tree-based Orthologycyanide metabolic processAT5G22300

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0016810 IEAInterProhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0000257 IDAUniProtnitrilase activity1
GO:0080109 IDAUniProtindole-3-acetonitrile nitrile hydratase activity1
GO:0080061 IDAUniProtindole-3-acetonitrile nitrilase activity1
GO:0047558 IEAPLAZA Tree-based Orthology3-cyanoalanine hydratase activityAT5G22300
GO:0018822 IEAPLAZA Tree-based Orthologynitrile hydratase activityAT5G22300
GO:0047427 IEAPLAZA Tree-based Orthologycyanoalanine nitrilase activityAT5G22300

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005886 IEA, ISM, UniProtplasma membrane1 2
GO:0005829 IDAUniProtcytosol1
GO:0009507 IEAPLAZA Integrative OrthologychloroplastAT3G44310
GO:0009506 IEAPLAZA Integrative OrthologyplasmodesmaAT3G44310
GO:0048046 IEAPLAZA Integrative OrthologyapoplastAT3G44310

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003010Carbon-nitrogen hydrolase
IPR000132Nitrilase/cyanide hydratase, conserved site

Mapman id Description
9.5.2.5.Secondary metabolism.glucosinolates.glucosinolate degradation.nitrilase
No SignalP domains detected for this gene.