Gene: AT3G19150 (Arabidopsis thaliana)

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Gene Identifier
AT3G19150
Transcript Identifier
AT3G19150.1
Gene Type
Coding gene
Location
Chr3 : 6616628-6617655 : negative

Family

Gene family
HOM04M001414
(104 genes in 25 species)
specific family
Duplication type
Block duplicate

Descriptions

Description
KIP-related protein 6
Curated Summary
Kip-related protein (KRP) gene, encodes CDK (cyclin-dependent kinase) inhibitor (CKI), negative regulator of cell division. Binds to D type cyclins. A member of seven KRP genes found in Arabidopsis thaliana. Differential expression patterns for distinct KRPs were revealed by in situ hybridization. KRP6 appears to be targeted for degradation by RHF1a and RHF2a to allow mitotic divisions during gametogenesis. In addition, KRP6 transcript levels rise prior to and drop following the meitotic divisions of gametogenesis. Elevated levels of KRP6 negatively affect plant development and fertility.
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Identifiers

Type Value
AliasACK1,ARABIDOPSIS CDK INHIBITOR 1,AtKRP6,ICK4
symbolKRP6
tidAT3G19150.1
UniProtQ0WNX9

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0007050 IEAUniProtcell cycle arrest1
GO:0042023 IMPGene OntologyDNA endoreduplication1 AGRICOLA_IND:IND23305253
GO:0045736 IDA, TAS, UniProtnegative regulation of cyclin-dependent protein serine/threonine kinase activity1 AGRICOLA_IND:IND233052532
GO:0010311 IEAPLAZA Tree-based Orthologylateral root formationAT2G23430
GO:0048527 IEAPLAZA Tree-based Orthologylateral root developmentAT2G23430
GO:0032877 IEAPLAZA Tree-based Orthologypositive regulation of DNA endoreduplicationAT3G24810
GO:0045740 IEAPLAZA Tree-based Orthologypositive regulation of DNA replicationAT2G23430
GO:0045786 IEAPLAZA Tree-based Orthologynegative regulation of cell cycleAT2G32710
GO:0000082 IEAPLAZA Tree-based OrthologyG1/S transition of mitotic cell cycleAT2G23430
GO:0048366 IEAPLAZA Tree-based Orthologyleaf developmentAT2G23430
GO:0048367 IEAPLAZA Tree-based Orthologyshoot system developmentAT2G23430
GO:0009737 IEAPLAZA Tree-based Orthologyresponse to abscisic acidAT2G23430

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004861 IEA, TAS, UniProtcyclin-dependent protein serine/threonine kinase inhibitor activity1 2 AGRICOLA_IND:IND23305253
GO:0030332 IPIGene Ontologycyclin binding1 AGRICOLA_IND:IND23305253
GO:0005515 IPIGene Ontologyprotein binding1
GO:0031490 IEAPLAZA Tree-based Orthologychromatin DNA bindingAT3G24810

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634 ISM, IEAGene Ontologynucleus1
GO:0005654 IEAUniProtnucleoplasm1
GO:0001673 IDAUniProtmale germ cell nucleus1
GO:0005737 IEAPLAZA Tree-based OrthologycytoplasmAT2G32710

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003175Cyclin-dependent kinase inhibitor

Mapman id Description
13.1.1.3.1.Cell cycle organisation.cell cycle control.cyclin-dependent regulation.cyclin-dependent protein kinase inhibitor activities.inhibitor (KRP/ICK)
No SignalP domains detected for this gene.