Gene: AT3G19050 (Arabidopsis thaliana)

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Gene Identifier
AT3G19050
Transcript Identifier
AT3G19050.1
Gene Type
Coding gene
Location
Chr3 : 6578047-6590106 : positive

Family

Gene family
HOM04M000020
(1960 genes in 29 species)
specific family
Subfamily
ORTHO04M000814
(140 genes in 29 species)
specific family

Descriptions

Description
phragmoplast orienting kinesin 2
Curated Summary
PHRAGMOPLAST ORIENTING KINESIN 2 is one of the two Arabidopsis homologs isolated in yeast two-hybrid screen for interaction partners of maize gene TANGLED1 (TAN1). Based on sequence homology in their motor domains, POK1 and POK2 belong to the kinesin-12 class which also includes the well-characterized group of phragmoplast-associated kinesins AtPAKRPs. Both kinesins are composed of an N-terminal motor domain throughout the entire C terminus and putative cargo binding tail domains. The expression domains for POK2 constructs were broader than those for POK1; both are expressed in tissues enriched for dividing cells. The phenotype of pok1/pok2 double mutants strongly resembles that of maize tan1 mutants, characterized by misoriented mitotic cytoskeletal arrays and misplaced cell walls.
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Identifiers

Type Value
symbolPOK2
tidAT3G19050.1
UniProtQ27IK6

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0007018 IBA, IEA, UniProtmicrotubule-based movement1
GO:0000281 IMPUniProtmitotic cytokinesis1 2
GO:0000911 IGIUniProtcytokinesis by cell plate formation1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0003777 IBA, ISS, IEA, UniProtmicrotubule motor activity1 2
GO:0005524 IEAUniProtATP binding1
GO:0008017 IEAUniProtmicrotubule binding1
GO:0016887 IBAUniProtATPase activity1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737 ISMGene Ontologycytoplasm1
GO:0005871 IBAUniProtkinesin complex1
GO:0005874 IEAUniProtmicrotubule1
GO:0009524 IEAUniProtphragmoplast1

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001752Kinesin motor domain
IPR019821Kinesin motor domain, conserved site
IPR027417P-loop containing nucleoside triphosphate hydrolase

Mapman id Description
13.4.3.7.Cell cycle organisation.cytokinesis.phragmoplast microtubule organization.phragmoplast integrity regulator (Kinesin-12)
20.1.3.10.Cytoskeleton organisation.microtubular network.Kinesin microtubule-based motor protein activities.motor protein (Kinesin-12)
No SignalP domains detected for this gene.