Gene: AT3G14980 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT3G14980
Transcript Identifier
AT3G14980.1
Gene Type
Coding gene
Location
Chr3 : 5039931-5044811 : negative

Family

Gene family
HOM04M000437
(264 genes in 29 species)
specific family

Descriptions

Description
Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger protein
Curated Summary
IDM1 is a histone H3 acetyltransferase that is capable of recognizing methylated DNA through its MBD domain and recognizing unmethylated histone H3K4 through its PHD domain. It negatively regulates DNA demethylation, preventing DNA hypermethylation of highly homologous multicopy genes and other repetitive sequences.
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Identifiers

Type Value
AliasIDM1,increased DNA methylation 1
full_nameREPRESSOR OF SILENCING 4
symbolROS4
tidAT3G14980.1
UniProtF4IXE7

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006355 IEA, ISS, UniProtregulation of transcription, DNA-templated1
GO:0043971 IDAUniProthistone H3-K18 acetylation1
GO:0043972 IDAUniProthistone H3-K23 acetylation1
GO:0044030 IMPUniProtregulation of DNA methylation1
GO:0044154 IDAUniProthistone H3-K14 acetylation1
GO:0080188 IMPUniProtRNA-directed DNA methylation1
GO:0006351 IEAUniProttranscription, DNA-templated

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0008080 IEAUniProtN-acetyltransferase activity
GO:0003677 ISSGene OntologyDNA binding1
GO:0004402 IDAUniProthistone acetyltransferase activity1
GO:0010385 IPIUniProtdouble-stranded methylated DNA binding1
GO:0042393 IDAUniProthistone binding1
GO:0046872 IEAUniProtmetal ion binding
GO:0016746 IEAUniProttransferase activity, transferring acyl groups

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634 IDA, ISM, ISS, UniProtnucleus1 2 3
GO:0009506 IDAUniProtplasmodesma1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR032308Jas TPL-binding domain
IPR019787Zinc finger, PHD-finger
IPR000182GNAT domain
IPR001841Zinc finger, RING-type
IPR001965Zinc finger, PHD-type
IPR011011Zinc finger, FYVE/PHD-type
IPR016181Acyl-CoA N-acyltransferase

Mapman id Description
12.5.3.2.2.Chromatin organisation.DNA methylation.ROS1-mediated DNA demethylation.ROS1-recruitment complex.component IDM1
15.5.30.RNA biosynthesis.transcriptional regulation.transcription factor (PHD)
No SignalP domains detected for this gene.