Gene: AT3G12280 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT3G12280
Transcript Identifier
AT3G12280.1
Gene Type
Coding gene
Location
Chr3 : 3913671-3918433 : negative

Family

Gene family
HOM04M002570
(63 genes in 29 species)
specific family

Descriptions

Description
retinoblastoma-related 1
Curated Summary
Encodes a retinoblastoma homologue RETINOBLASTOMA-RELATED protein (RBR or RBR1). RBR controls nuclear proliferation in the female gametophyte. Also required for correct differentiation of male gametophytic cell types. Regulates stem cell maintenance in Arabidopsis roots. Involved in the determination of cell cycle arrest in G1 phase after sucrose starvation. RBR1 is also involved in regulation of imprinted genes. Together with MSI1 it represses the expression of MET1. This in turn activates expression of the imprinted genes FIS2 and FWA. Functions as a positive regulator of the developmental switch from embryonic heterotrophic growth to autotrophic growth
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Identifiers

Type Value
AliasATRBR1,RETINOBLASTOMA-RELATED PROTEIN 1,RB,RB1,RETINOBLASTOMA 1,RBR,RETINOBLASTOMA-RELATED
symbolRBR1
tidAT3G12280.1
UniProtQ9LKZ3

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006357 IEAUniProtregulation of transcription from RNA polymerase II promoter1
GO:0051726 IEA, IMPUniProtregulation of cell cycle1 2
GO:0006351 IEAUniProttranscription, DNA-templated1
GO:0007049 IEAUniProtcell cycle1
GO:0016032 IEAUniProtviral process1
GO:0051783 IMPUniProtregulation of nuclear division1
GO:0010090 IMPUniProttrichome morphogenesis1
GO:0032875 IMPUniProtregulation of DNA endoreduplication1
GO:0048366 IMPUniProtleaf development1
GO:0001558 IMPUniProtregulation of cell growth1
GO:2000036 IMPUniProtregulation of stem cell population maintenance1
GO:0009553 IMPUniProtembryo sac development1
GO:0009567 IEPUniProtdouble fertilization forming a zygote and endosperm1
GO:0000082 IMP, TAS, UniProtG1/S transition of mitotic cell cycle1 2
GO:0006349 IPIUniProtregulation of gene expression by genetic imprinting1
GO:2000653 IDAUniProtregulation of genetic imprinting1
GO:0009555 IMPUniProtpollen development1
GO:0022619 IMPUniProtgenerative cell differentiation1
GO:0030154 IMPUniProtcell differentiation1
GO:0048229 IMPUniProtgametophyte development1
GO:0001708 IMPUniProtcell fate specification1
GO:0007129 IMPUniProtsynapsis1 2
GO:0008356 IMP, IGI, UniProtasymmetric cell division1 2 3
GO:1903866 IMPUniProtpalisade mesophyll development1 2
GO:0010377 IGIUniProtguard cell fate commitment1 2

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005515 IPIGene Ontologyprotein binding1 2
GO:0003677 IDAUniProtDNA binding1
GO:0008134 TASUniProttranscription factor binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634 IDA, IEA, ISM, UniProtnucleus1 2 3 4
GO:0005829 IDAUniProtcytosol1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR013763Cyclin-like
IPR028309Retinoblastoma protein family
IPR015652Retinoblastoma-related protein
IPR002720Retinoblastoma-associated protein, A-box
IPR002719Retinoblastoma-associated protein, B-box
IPR024599Retinoblastoma-associated protein, N-terminal
IPR015030Retinoblastoma-associated protein, C-terminal

Mapman id Description
13.1.2.1.Cell cycle organisation.cell cycle control.regulation.key regulator (RBR)
No SignalP domains detected for this gene.