PLAZA 4.0 Monocots gene overview : AT3G07610

Gene: AT3G07610 (Arabidopsis thaliana)

Curated Summary: IBM1 likely encodes a protein with histone H3mK9 demethylation activity. It may preferentially demethylate H3mK9 at low-copy loci to protect them from silencing by nearby heterochromatin by preventing the spread of cytosine methylation. BONSAI (At1g73177) is hypermethylated in ibm1 mutants. ibm1 mutants have morphological defects that become apparent at the F3 generation, including small narrow leaves, arrested flower development, and faulty pollen development. These phenotypes cannot result solely from the BONSAI hypermethylation. Aberrant phenotypes in ibm1 mutants in both DNA methylation and plant development can be suppressed by mutations in the KYP H3K9 methyltransferase or he CMT3 non CG-cytosine methylase.

Type	Value
full_name	increase in bonsai methylation 1
symbol	IBM1
tid	AT3G07610.1
UniProt	Q9SSE9

GO term	Evidence(s)	Provider	Description	Source
GO:0006351	IEA	UniProt	transcription, DNA-templated	1
GO:0006355	IEA	UniProt	regulation of transcription, DNA-templated	1
GO:0055114	IEA	Gene Ontology	oxidation-reduction process	1
GO:0009555	IMP	UniProt	pollen development	1
GO:0009908	IMP	UniProt	flower development	1
GO:0032776	IMP, IGI	UniProt	DNA methylation on cytosine	1 2
GO:0033169	IMP, IGI	UniProt	histone H3-K9 demethylation	1 2
GO:0048366	IMP	UniProt	leaf development	1
GO:0010468	IMP	UniProt	regulation of gene expression	1
GO:0060969	IMP	UniProt	negative regulation of gene silencing	1
GO:0070919	IMP	UniProt	production of siRNA involved in chromatin silencing by small RNA	1
GO:0080188	IMP	UniProt	RNA-directed DNA methylation	1

GO term	Evidence(s)	Provider	Description	Source
GO:0000976	IBA	UniProt	transcription regulatory region sequence-specific DNA binding	1
GO:0003700	ISS	Gene Ontology	transcription factor activity, sequence-specific DNA binding	1
GO:0046872	IEA	UniProt	metal ion binding	1
GO:0051213	IEA	UniProt	dioxygenase activity	1
GO:0032454	IDA, IMP, ISS,	UniProt	histone demethylase activity (H3-K9 specific)	1 2 3 4
GO:0031490	IDA	UniProt	chromatin DNA binding	1

GO term	Evidence(s)	Provider	Description	Source
GO:0000785	IBA	UniProt	chromatin	1
GO:0005634	IBA, ISM,	UniProt	nucleus	1 2

Experimental Evidence

Electronic Evidence

Computational Reviewed Evidence

InterPro	Description
IPR003347	JmjC domain

Mapman id	Description
12.3.3.9.1	.Chromatin organisation.histone modifications.histone lysine methylation.JmjC group histone demethylase activities.histone demethylase (KDM3)
15.5.29	.RNA biosynthesis.transcriptional regulation.transcription factor (JUMONJI)

No SignalP domains detected for this gene.