Gene: AT3G06860 (Arabidopsis thaliana)

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Gene Identifier
AT3G06860
Transcript Identifier
AT3G06860.1
Gene Type
Coding gene
Location
Chr3 : 2161926-2166009 : positive

Family

Gene family
HOM04M000571
(215 genes in 29 species)
specific family
Subfamily
ORTHO04M001270
(104 genes in 29 species)
specific family

Descriptions

Description
multifunctional protein 2
Curated Summary
Encodes a multifunctional protein. Involved in peroxisomal fatty acid beta oxidation. Loss-of-function mutant lacks hydroxyacyl-CoA dehydrogenase activity and have reduced levels of long-chain enoyl-CoA hydratase activity. The mutant has fewer but larger peroxisomes.
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Identifiers

Type Value
AliasATMFP2,MULTIFUNCTIONAL PROTEIN 2
symbolMFP2
tidAT3G06860.1
UniProtQ9ZPI5

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0055114 IEAInterProoxidation-reduction process
GO:0006631 IEAInterProfatty acid metabolic process
GO:0008152 IEAInterPrometabolic process
GO:0006635 IEP, IEAUniProtfatty acid beta-oxidation1 2

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0016491 IEAInterProoxidoreductase activity
GO:0003857 IDA, IMPIEA, UniProt3-hydroxyacyl-CoA dehydrogenase activity1 2
GO:0003824 IEAInterProcatalytic activity
GO:0004165 IEAUniProtdodecenoyl-CoA delta-isomerase activity1
GO:0004300 IEA, IMP, UniProtenoyl-CoA hydratase activity1 2
GO:0008692 IEAUniProt3-hydroxybutyryl-CoA epimerase activity1
GO:0016508 IDAUniProtlong-chain-enoyl-CoA hydratase activity1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737 ISMGene Ontologycytoplasm1
GO:0009514 IEAUniProtglyoxysome1
GO:0005777 IDA, TAS, UniProtperoxisome1 2
GO:0005730 IDAUniProtnucleolus1
GO:0005618 IDAUniProtcell wall1
GO:0005829 RCAGene Ontologycytosol1
GO:0009506 IDAUniProtplasmodesma1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR0133286-phosphogluconate dehydrogenase, domain 2
IPR0061763-hydroxyacyl-CoA dehydrogenase, NAD binding
IPR0061083-hydroxyacyl-CoA dehydrogenase, C-terminal
IPR001753Crotonase superfamily
IPR0061803-hydroxyacyl-CoA dehydrogenase, conserved site
IPR018376Enoyl-CoA hydratase/isomerase, conserved site
IPR016040NAD(P)-binding domain
IPR0089276-phosphogluconate dehydrogenase C-terminal domain-like
IPR029045ClpP/crotonase-like domain

Mapman id Description
5.7.3.2.2.Lipid metabolism.lipid degradation.fatty acid degradation.core beta-oxidation.multifunctional enzyme (MFP)
No SignalP domains detected for this gene.