Gene: AT3G06483 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT3G06483
Transcript Identifier
AT3G06483.1
Gene Type
Coding gene
Location
Chr3 : 1990727-1992581 : negative

Family

Gene family
HOM04M002423
(67 genes in 29 species)
specific family
Subfamily
ORTHO04M003482
(55 genes in 29 species)
specific family

Descriptions

Description
pyruvate dehydrogenase kinase
Curated Summary
Pyruvate dehydrogenase kinase (PDK) specifically phosphorylates the E1α subunit of the pyruvate dehydrogenase complex (PDC) on a Ser residue using ATP as a phosphate donor. PDK is a unique type of protein kinase having a His-kinase-like sequence but Ser-kinase activity. Site-directed mutagenesis and structural analysis indicate that PDK belongs to the GHKL superfamily.
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Identifiers

Type Value
AliasATPDHK
symbolPDK
tidAT3G06483.1
UniProtQ9SBJ1

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0016310 IEAInterProphosphorylation
GO:0046777 IDAUniProtprotein autophosphorylation1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0016772 IEAInterProtransferase activity, transferring phosphorus-containing groups
GO:0004740 IEA, IMP, UniProtpyruvate dehydrogenase (acetyl-transferring) kinase activity1 2
GO:0005524 IDA, ISS, UniProtATP binding1 2
GO:0009927 IDAUniProthistidine phosphotransfer kinase activity1
GO:0042803 IPIUniProtprotein homodimerization activity1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005739 NAS, ISM, UniProtmitochondrion1 2

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR018955Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal
IPR003594Histidine kinase-like ATPase, C-terminal domain
IPR004358Signal transduction histidine kinase-related protein, C-terminal
IPR005467Histidine kinase domain

Mapman id Description
2.2.1.4.1.Cellular respiration.pyruvate oxidation.mitochondrial pyruvate dehydrogenase complex.regulation.pyruvate dehydrogenase kinase
No SignalP domains detected for this gene.