Gene: AT3G04740 (Arabidopsis thaliana)

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Gene Identifier
AT3G04740
Transcript Identifier
AT3G04740.1
Gene Type
Coding gene
Location
Chr3 : 1294037-1300555 : positive

Family

Gene family
HOM04M002164
(73 genes in 29 species)
specific family

Descriptions

Description
RNA polymerase II transcription mediator
Curated Summary
encodes a protein with similarities to subunits of the Mediator complex, required for RNA polymerase II recruitment at target promoters in response to specific activators. Lines carrying loss of function mutations in the gene have reduced cell numbers in aerial organs. On the other hand, lines overexpressing the gene have increased number of small cells in clusters, suggesting cell division is more unsynchronized in the overexpressors.Required for expression of CBF-controlled cold-responsive genes. Required for recruitment of the Mediator complex and RNA polymerase II to CBF-controlled cold-responsive genes. Required for expression of some dark-upregulated genes.
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Identifiers

Type Value
AliasATMED14,ARABIDOPSIS MEDIATOR COMPONENTS 14,MED14,MEDIATOR COMPONENTS 14
full_nameSTRUWWELPETER
symbolSWP
tidAT3G04740.1
UniProtQ9SR02

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006357 IEAGene Ontologyregulation of transcription from RNA polymerase II promoter1
GO:0006351 IEAUniProttranscription, DNA-templated1
GO:0007275 IEAUniProtmulticellular organism development1
GO:0040008 IEAUniProtregulation of growth1
GO:0008284 IMPUniProtpositive regulation of cell proliferation1
GO:0045893 ISSGene Ontologypositive regulation of transcription, DNA-templated1
GO:0009627 IEPUniProtsystemic acquired resistance1
GO:0009631 IMPUniProtcold acclimation1 2

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0001104 IBA, IEA, UniProtRNA polymerase II transcription cofactor activity1
GO:0005515 IPIGene Ontologyprotein binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0016592 IDA, ISSIEA, UniProtmediator complex1 2
GO:0005634 ISMGene Ontologynucleus1
GO:0070847 IBAUniProtcore mediator complex1
GO:0009506 IDAUniProtplasmodesma1

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR013947Mediator complex, subunit Med14

Mapman id Description
15.3.3.3.4.RNA biosynthesis.RNA polymerase II-dependent transcription.MEDIATOR transcription co-activator complex.tail module.component MED14
No SignalP domains detected for this gene.