Gene: AT2G45140 (Arabidopsis thaliana)

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Gene Identifier
AT2G45140
Transcript Identifier
AT2G45140.1
Gene Type
Coding gene
Location
Chr2 : 18611029-18612971 : positive

Family

Gene family
HOM04M000421
(272 genes in 29 species)
specific family
Duplication type
Block duplicate

Descriptions

Description
plant VAP homolog 12
Curated Summary
Encodes a Plant VAMP-Associated protein that localizes to the ER and binds to the sitosterol-binding protein ORP3a. The WFDE motif in ORP3a appears to be important for this direct interaction. Mutation of this motif causes ORP3a to relocalize to the Golgi and cytosol. The interaction between PVA12 and ORP3a does not appear to be sterol-dependent.
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Identifiers

Type Value
symbolPVA12
tidAT2G45140.1
UniProtQ9SHC8

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006605 IDAUniProtprotein targeting1
GO:0046907 IEAPLAZA Integrative Orthologyintracellular transportAT3G60600

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005198 ISSGene Ontologystructural molecule activity1
GO:0005515 IPIGene Ontologyprotein binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005789 IEAUniProtendoplasmic reticulum membrane1
GO:0016021 IEAUniProtintegral component of membrane1
GO:0005886 IDAUniProtplasma membrane1
GO:0005783 IDAUniProtendoplasmic reticulum1
GO:0005634 IDAUniProtnucleus1
GO:0005829 IDAUniProtcytosol1
GO:0005622 IDAGene Ontologyintracellular1
GO:0005623 IDAGene Ontologycell1
GO:0000326 IEAPLAZA Integrative Orthologyprotein storage vacuoleAT3G60600

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR013783Immunoglobulin-like fold
IPR016763Vesicle-associated membrane-protein-associated protein
IPR000535Major sperm protein (MSP) domain
IPR008962PapD-like

Mapman id Description
20.7.1.Cytoskeleton organisation.endoplasmic reticulum-cytoskeleton-plasma membrane interface.contact site protein (VAP27)
No SignalP domains detected for this gene.