Gene: AT2G35020 (Arabidopsis thaliana)

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Gene Identifier
AT2G35020
Transcript Identifier
AT2G35020.1
Gene Type
Coding gene
Location
Chr2 : 14756803-14760477 : positive

Family

Gene family
HOM04M002832
(58 genes in 29 species)
specific family
Duplication type
Block duplicate

Descriptions

Description
N-acetylglucosamine-1-phosphate uridylyltransferase 2
Curated Summary
Encodes a protein that functions as an N-acetylglucosamine-1-phosphate uridylyltransferase that catalyzes the formation of UDP-N-acetylglucosamine (UDP-GlcNAc). This is an essential precursor for glycolipid and glycoprotein synthesis and is also used for regulatory protein modification in signaling pathways. The enzyme can also catalyze the reverse reaction using both UDP-GlcNAc and the less common UDP-N-acetylgalactosamine as substrates. This enzyme can also act on glucose-1-phosphate to produce UDP-glucose.
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Identifiers

Type Value
AliasGLCNA.UT2,N-acetylglucosamine-1-phosphate uridylyltransferase 2
symbolGlcNAc1pUT2
tidAT2G35020.1
UniProtO64765

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0008152 IEAInterPrometabolic process
GO:0006048 IBA, IEAGene OntologyUDP-N-acetylglucosamine biosynthetic process1 2
GO:0006011 IDAGene OntologyUDP-glucose metabolic process1
GO:0006047 IDAGene OntologyUDP-N-acetylglucosamine metabolic process1
GO:0019276 IDAGene OntologyUDP-N-acetylgalactosamine metabolic process1
GO:0009553 IMPGene Ontologyembryo sac development1 2
GO:0009555 IMPGene Ontologypollen development1 2
GO:0009793 IMPGene Ontologyembryo development ending in seed dormancy1 2

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0070569 IEAInterProuridylyltransferase activity
GO:0016779 ISSGene Ontologynucleotidyltransferase activity1
GO:0003977 IDAGene OntologyUDP-N-acetylglucosamine diphosphorylase activity1
GO:0003983 IDAGene OntologyUTP:glucose-1-phosphate uridylyltransferase activity1
GO:0052630 IDAGene OntologyUDP-N-acetylgalactosamine diphosphorylase activity1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737 ISMGene Ontologycytoplasm1
GO:0005829 IBA, RCAGene Ontologycytosol1 2
GO:0005886 IEAPLAZA Integrative Orthologyplasma membraneAT1G31070

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR029044Nucleotide-diphospho-sugar transferases
IPR002618UDPGP family

Mapman id Description
3.13.9.1.4.Carbohydrate metabolism.nucleotide sugar biosynthesis.UDP-N-acetylglucosamine biosynthesis.de novo biosynthesis.UDP-N-acetylglucosamine pyrophosphorylase
No SignalP domains detected for this gene.