Gene: AT2G29890 (Arabidopsis thaliana)

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Gene Identifier
AT2G29890
Transcript Identifier
AT2G29890.4
Gene Type
Coding gene
Location
Chr2 : 12744597-12749474 : positive

Family

Gene family
HOM04M000675
(190 genes in 29 species)
specific family
Subfamily
ORTHO04M000561
(179 genes in 29 species)
specific family

Descriptions

Description
villin-like 1
Curated Summary
Encodes a ubiquitously expressed villin-like protein, whose mRNA may be alternatively processed. Villin belongs to a superfamily of actin binding proteins called the villin/gelsolin family. Animal villins are involved in actin binding. VLN1 protein co-localizes with actin filaments in several assays. VLN1 binds and bundles F-actin in a calcium-independent manner. It does not nucleate, cap or sever actin filaments and it stabilizes actin filaments, protecting them from ADF-mediated depolymerization.
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Identifiers

Type Value
AliasATVLN1
full_namevillin 1
symbolVLN1
tidAT2G29890.4

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0007010 ISS, IEAGene Ontologycytoskeleton organization1
GO:0051017 IEAUniProtactin filament bundle assembly1
GO:0051693 IEAUniProtactin filament capping1
GO:0007015 IPIGene Ontologyactin filament organization1
GO:0030042 IDAGene Ontologyactin filament depolymerization1
GO:0030835 IDAUniProtnegative regulation of actin filament depolymerization1
GO:0045010 IDAGene Ontologyactin nucleation1
GO:0051014 IDAGene Ontologyactin filament severing1
GO:0051016 IDAGene Ontologybarbed-end actin filament capping1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0003779 IDA, IEAISS, UniProtactin binding1 2 3
GO:0051015 IEA, IPI, UniProtactin filament binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737 IEA, ISM, UniProtcytoplasm1 2
GO:0005856 IEAUniProtcytoskeleton1
GO:0015629 IDAUniProtactin cytoskeleton1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003128Villin headpiece
IPR029006ADF-H/Gelsolin-like domain
IPR030010Villin-1, plant
IPR007122Villin/Gelsolin
IPR007123Gelsolin-like domain

Mapman id Description
20.2.2.5.Cytoskeleton organisation.microfilament network.actin polymerisation.villin actin-crosslinking factor
No SignalP domains detected for this gene.