Gene: AT2G23430 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT2G23430
Transcript Identifier
AT2G23430.1
Gene Type
Coding gene
Location
Chr2 : 9977020-9977921 : negative

Family

Gene family
HOM04M001414
(104 genes in 25 species)
specific family

Descriptions

Description
Cyclin-dependent kinase inhibitor family protein
Curated Summary
Encodes a cyclin-dependent kinase inhibitor protein that functions as a negative regulator of cell division and promoter of endoreduplication. A member of seven KRP genes found in Arabidopsis thaliana. Differential expression patterns for distinct KRPs were revealed by in situ hybridization. Both SKP2b and RKP appear to be involved in the degradation of KRP1.
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Identifiers

Type Value
symbolICK1
tidAT2G23430.1
UniProtQ67Y93

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0007050 IEAUniProtcell cycle arrest1
GO:0010102 NASGene Ontologylateral root morphogenesis1
GO:0045740 IMPUniProtpositive regulation of DNA replication1
GO:0045736 IDA, ISS, UniProtnegative regulation of cyclin-dependent protein serine/threonine kinase activity1 2
GO:0000082 TASUniProtG1/S transition of mitotic cell cycle1
GO:0010311 IMPUniProtlateral root formation1
GO:0048366 IMPUniProtleaf development1
GO:0048367 IMPUniProtshoot system development1
GO:0048527 IMPUniProtlateral root development1
GO:0009737 IEPUniProtresponse to abscisic acid1
GO:0032877 IEAPLAZA Tree-based Orthologypositive regulation of DNA endoreduplicationAT3G24810
GO:0042023 IEAPLAZA Tree-based OrthologyDNA endoreduplicationAT3G19150
GO:0045786 IEAPLAZA Tree-based Orthologynegative regulation of cell cycleAT2G32710

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004861 IDA, IMP, ISS, IEA, UniProtcyclin-dependent protein serine/threonine kinase inhibitor activity1 2 3
GO:0005515 IPIGene Ontologyprotein binding1
GO:0030332 IEAPLAZA Tree-based Orthologycyclin bindingAT1G49620
GO:0031490 IEAPLAZA Tree-based Orthologychromatin DNA bindingAT3G24810

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634 IDA, ISM, IEA, UniProtnucleus1 2
GO:0005654 IEAUniProtnucleoplasm1
GO:0001673 IEAPLAZA Tree-based Orthologymale germ cell nucleusAT1G49620
GO:0005737 IEAPLAZA Tree-based OrthologycytoplasmAT2G32710

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003175Cyclin-dependent kinase inhibitor

Mapman id Description
13.1.1.3.1.Cell cycle organisation.cell cycle control.cyclin-dependent regulation.cyclin-dependent protein kinase inhibitor activities.inhibitor (KRP/ICK)
No SignalP domains detected for this gene.