Gene: AT2G22780 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT2G22780
Transcript Identifier
AT2G22780.1
Gene Type
Coding gene
Location
Chr2 : 9689995-9691923 : negative

Family

Gene family
HOM04M000628
(200 genes in 29 species)
specific family
Subfamily
ORTHO04M001087
(116 genes in 29 species)
specific family

Descriptions

Description
peroxisomal NAD-malate dehydrogenase 1
Curated Summary
encodes an peroxisomal NAD-malate dehydrogenase that is involved in fatty acid beta-oxidation through providing NAD to the process of converting fatty acyl CoA to acetyl CoA.
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Identifiers

Type Value
symbolPMDH1
tidAT2G22780.1
UniProtO82399

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0055114 IEAInterProoxidation-reduction process
GO:0019752 IEAInterProcarboxylic acid metabolic process
GO:0006108 IEAUniProtmalate metabolic process1
GO:0005975 IEAInterProcarbohydrate metabolic process
GO:0006099 IEAUniProttricarboxylic acid cycle1
GO:0006097 IEAUniProtglyoxylate cycle1
GO:0031998 IMP, IGIUniProtregulation of fatty acid beta-oxidation1 2
GO:0080093 IMPUniProtregulation of photorespiration1
GO:0009735 IEAPLAZA Tree-based Orthologyresponse to cytokininAT5G09660

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0016616 IEAInterProoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0016491 IEAInterProoxidoreductase activity
GO:0016615 ISS, IEAGene Ontologymalate dehydrogenase activity1
GO:0003824 IEAInterProcatalytic activity
GO:0030060 IEAUniProtL-malate dehydrogenase activity1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737 ISMGene Ontologycytoplasm1
GO:0005777 IDAUniProtperoxisome1
GO:0009507 IDAUniProtchloroplast1
GO:0005773 IEAPLAZA Tree-based OrthologyvacuoleAT5G09660
GO:0009941 IEAPLAZA Tree-based Orthologychloroplast envelopeAT5G09660
GO:0048046 IEAPLAZA Tree-based OrthologyapoplastAT5G09660

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR022383Lactate/malate dehydrogenase, C-terminal
IPR001236Lactate/malate dehydrogenase, N-terminal
IPR001557L-lactate/malate dehydrogenase
IPR001252Malate dehydrogenase, active site
IPR016040NAD(P)-binding domain
IPR015955Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
IPR010097Malate dehydrogenase, type 1

Mapman id Description
5.7.3.6.5.Lipid metabolism.lipid degradation.fatty acid degradation.glyoxylate cycle.peroxisomal NAD-dependent malate dehydrogenase
No SignalP domains detected for this gene.