Gene: AT2G20990 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT2G20990
Transcript Identifier
AT2G20990.1
Gene Type
Coding gene
Location
Chr2 : 9014827-9017829 : positive

Family

Gene family
HOM04M000429
(266 genes in 29 species)
specific family
Subfamily
ORTHO04M000336
(255 genes in 29 species)
specific family
Duplication type
Tandem duplicate

Descriptions

Description
synaptotagmin A
Curated Summary
Encodes a plasma membrane localized protein with similarity to synaptotagmins, a class of membrane trafficking proteins. SYT1 is expressed in all tissues. Loss of function mutations show hypersensitivity to NaCl and electrolyte leakage from the plasma membrane. SYT1 also affects calcium dependent freezing tolerance. SYT1 probably plays a role in membrane repair such as membrane resealing after freezing induced damage. Regulates endocytosis endosome recycling at the plasma membrane, but not membrane traffic along the secretory pathway.
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Identifiers

Type Value
AliasATSYTA,ARABIDOPSIS THALIANA SYNAPTOTAGMIN A,NTMC2T1.1,NTMC2TYPE1.1,SYT1,SYNAPTOTAGMIN 1
symbolSYTA
tidAT2G20990.1
UniProtQ9SKR2

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006897 IEA, IMP, UniProtendocytosis1 2
GO:0016032 IEAUniProtviral process1
GO:0006612 ISSUniProtprotein targeting to membrane1
GO:0001778 IMPUniProtplasma membrane repair1
GO:0009409 IMPUniProtresponse to cold1
GO:0009615 IPIGene Ontologyresponse to virus1
GO:0032456 IMPUniProtendocytic recycling1
GO:0046740 IMPUniProttransport of virus in host, cell to cell1
GO:0009612 IMPUniProtresponse to mechanical stimulus1 2

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0008289 IEAUniProtlipid binding1
GO:0046872 IEAUniProtmetal ion binding1
GO:1901981 IDAUniProtphosphatidylinositol phosphate binding1 2

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005886 IDA, IEA, ISM, UniProtplasma membrane1 2 3
GO:0010008 IEAUniProtendosome membrane1
GO:0016021 IEAUniProtintegral component of membrane1
GO:0005773 IDAUniProtvacuole1
GO:0016020 IDAUniProtmembrane1
GO:0009898 IDAUniProtcytoplasmic side of plasma membrane1
GO:0005768 IDAUniProtendosome1
GO:0009506 IDAUniProtplasmodesma1
GO:0005783 IDAUniProtendoplasmic reticulum1
GO:0032541 IDAUniProtcortical endoplasmic reticulum1 2

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000008C2 domain
IPR031468Synaptotagmin-like mitochondrial-lipid-binding domain

Mapman id Description
5.8.1.2.Lipid metabolism.lipid trafficking.endoplasmic reticulum-plasma membrane lipid transfer.endoplasmic reticulum-plasma membrane tethering protein (SYTa/b/c)
No SignalP domains detected for this gene.