PLAZA 4.0 Monocots gene overview : AT2G20990

Gene: AT2G20990 (Arabidopsis thaliana)

Curated Summary: Encodes a plasma membrane localized protein with similarity to synaptotagmins, a class of membrane trafficking proteins. SYT1 is expressed in all tissues. Loss of function mutations show hypersensitivity to NaCl and electrolyte leakage from the plasma membrane. SYT1 also affects calcium dependent freezing tolerance. SYT1 probably plays a role in membrane repair such as membrane resealing after freezing induced damage. Regulates endocytosis endosome recycling at the plasma membrane, but not membrane traffic along the secretory pathway.

Type	Value
Alias	ATSYTA,ARABIDOPSIS THALIANA SYNAPTOTAGMIN A,NTMC2T1.1,NTMC2TYPE1.1,SYT1,SYNAPTOTAGMIN 1
symbol	SYTA
tid	AT2G20990.1
UniProt	Q9SKR2

GO term	Evidence(s)	Provider	Description	Source
GO:0006897	IEA, IMP,	UniProt	endocytosis	1 2
GO:0016032	IEA	UniProt	viral process	1
GO:0006612	ISS	UniProt	protein targeting to membrane	1
GO:0001778	IMP	UniProt	plasma membrane repair	1
GO:0009409	IMP	UniProt	response to cold	1
GO:0009615	IPI	Gene Ontology	response to virus	1
GO:0032456	IMP	UniProt	endocytic recycling	1
GO:0046740	IMP	UniProt	transport of virus in host, cell to cell	1
GO:0009612	IMP	UniProt	response to mechanical stimulus	1 2

GO term	Evidence(s)	Provider	Description	Source
GO:0008289	IEA	UniProt	lipid binding	1
GO:0046872	IEA	UniProt	metal ion binding	1
GO:1901981	IDA	UniProt	phosphatidylinositol phosphate binding	1 2

GO term	Evidence(s)	Provider	Description	Source
GO:0005886	IDA, IEA, ISM,	UniProt	plasma membrane	1 2 3
GO:0010008	IEA	UniProt	endosome membrane	1
GO:0016021	IEA	UniProt	integral component of membrane	1
GO:0005773	IDA	UniProt	vacuole	1
GO:0016020	IDA	UniProt	membrane	1
GO:0009898	IDA	UniProt	cytoplasmic side of plasma membrane	1
GO:0005768	IDA	UniProt	endosome	1
GO:0009506	IDA	UniProt	plasmodesma	1
GO:0005783	IDA	UniProt	endoplasmic reticulum	1
GO:0032541	IDA	UniProt	cortical endoplasmic reticulum	1 2

Experimental Evidence

Electronic Evidence

Computational Reviewed Evidence

InterPro	Description
IPR000008	C2 domain
IPR031468	Synaptotagmin-like mitochondrial-lipid-binding domain

Mapman id	Description
5.8.1.2	.Lipid metabolism.lipid trafficking.endoplasmic reticulum-plasma membrane lipid transfer.endoplasmic reticulum-plasma membrane tethering protein (SYTa/b/c)

No SignalP domains detected for this gene.