Gene: AT1G77000 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G77000
Transcript Identifier
AT1G77000.2
Gene Type
Coding gene
Location
Chr1 : 28940888-28942401 : positive

Family

Gene family
HOM04M002643
(61 genes in 28 species)
specific family
Duplication type
Block duplicate

Descriptions

Description
RNI-like superfamily protein
Curated Summary
AtSKP2;2 is a homolog of human SKP2, the human F-box protein that recruits E2F1. Contains an F-box motif at the N-terminal region and a C-terminal Leu-rich repeat domain. Forms part of an E3-ubiquitin-ligase SCF (Skp1, cullin, F-box) complex and recruits phosphorylated AtE2Fc, a transcriptional factor that might play a role in cell division and during the transition from skotomorphogenesis to photomorphogenesis. AtSKP2;1 (At1g21410) and AtSKP2;2 (At1g77000) may be duplicated genes. AtSKP2b may also be involved in the degradation of KRP1/ICK1, a CDK inhibitor.
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Identifiers

Type Value
symbolSKP2B
tidAT1G77000.2
UniProtO49286

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006511 TASGene Ontologyubiquitin-dependent protein catabolic process1
GO:0010286 IEPUniProtheat acclimation1
GO:0051603 IMPUniProtproteolysis involved in cellular protein catabolic process1
GO:1901332 IMPUniProtnegative regulation of lateral root development1
GO:0051781 IEAPLAZA Integrative Orthologypositive regulation of cell divisionAT1G21410
GO:0071365 IEAPLAZA Integrative Orthologycellular response to auxin stimulusAT1G21410
GO:0031146 IEAPLAZA Integrative OrthologySCF-dependent proteasomal ubiquitin-dependent protein catabolic processAT1G21410
GO:0016567 IEAPLAZA Integrative Orthologyprotein ubiquitinationAT1G21410
GO:0010311 IEAPLAZA Integrative Orthologylateral root formationAT1G21410

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005515 IEAInterProprotein binding
GO:0004842 ISSGene Ontologyubiquitin-protein transferase activity1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634 ISMGene Ontologynucleus1
GO:0019005 IEAPLAZA Integrative OrthologySCF ubiquitin ligase complexAT1G21410

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR032675Leucine-rich repeat domain, L domain-like
IPR001611Leucine-rich repeat
IPR001810F-box domain
IPR006553Leucine-rich repeat, cysteine-containing subtype

Mapman id Description
19.2.2.8.1.4.1.Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.SKP1-CUL1-FBX (SCF) E3 ligase complexes.F-BOX substrate adaptor components.component SKP2
No SignalP domains detected for this gene.