Gene: AT1G68310 (Arabidopsis thaliana)

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Gene Identifier
AT1G68310
Transcript Identifier
AT1G68310.2
Gene Type
Coding gene
Location
Chr1 : 25599812-25601239 : positive

Family

Gene family
HOM04M002263
(70 genes in 28 species)
specific family
Subfamily
ORTHO04M002643
(66 genes in 28 species)
specific family

Descriptions

Description
MIP18 family protein (DUF59)
Curated Summary
Encodes a protein that has been shown to specifically interact with a sequence motif, PIEPPPHH, in the cytoplasmic tail of a membrane protein that directs the protein from the ER to vacuoles where it is internalized. Required for both leaf adaxial–abaxial polarity formation and normal cell proliferation. It is part of a protein complex with CIA1, NAR1, and MET18, which are highly conserved in eukaryotes and are involved in the biogenesis of cytosolic and nuclear Fe-S proteins.
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Identifiers

Type Value
full_nameAS1/2 ENHANCER7
symbolAE7
tidAT1G68310.2
UniProtQ9C9G6

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0007059 IEAUniProtchromosome segregation1
GO:0009944 IMPUniProtpolarity specification of adaxial/abaxial axis1
GO:0042127 IMPUniProtregulation of cell proliferation1
GO:0051726 IMPUniProtregulation of cell cycle1
GO:0006259 IMPUniProtDNA metabolic process1
GO:0016226 IMPUniProtiron-sulfur cluster assembly1
GO:1990067 IMPUniProtintrachromosomal DNA recombination1
GO:2001022 IMPUniProtpositive regulation of response to DNA damage stimulus1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0010209 IDAUniProtvacuolar sorting signal binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634 IEA, ISM, UniProtnucleus1 2
GO:0005737 IEAUniProtcytoplasm1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR034904Fe-S cluster assembly domain
IPR002744MIP18 family-like

Mapman id Description
7.11.3.2.2.Coenzyme metabolism.iron-sulfur cluster assembly machinery.cytosolic CIA system.transfer phase.carrier protein (CIA2/AE7)
No SignalP domains detected for this gene.