Gene: AT1G65060 (Arabidopsis thaliana)

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Gene Identifier
AT1G65060
Transcript Identifier
AT1G65060.1
Gene Type
Coding gene
Location
Chr1 : 24167385-24171457 : negative

Family

Gene family
HOM04M000185
(503 genes in 27 species)
specific family
Subfamily
ORTHO04M000924
(130 genes in 27 species)
specific family

Descriptions

Curated Summary
encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. mRNA levels are not induced in response to wounding or to fungal infection by P. parasitica. mRNA is expressed in flowers, to a lesser degree in mature leaves and siliques and marginally in seedling roots and bolting stems of mature plants. The catalytic efficiency was in the following (descending) order: p-coumaric acid, caffeic acid, ferulic acid, cinnamic acid and 5-OH-ferulic acid. At4CL3 was unable to use sinapic acid as substrate.
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Identifiers

Type Value
symbol4CL3
tidAT1G65060.1
UniProtQ9S777

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0008152 IEAUniProtmetabolic process1
GO:0010584 IMPUniProtpollen exine formation1
GO:0009411 IEPGene Ontologyresponse to UV1
GO:0009611 IEPGene Ontologyresponse to wounding1
GO:0009698 TASUniProtphenylpropanoid metabolic process1
GO:0050832 IEPGene Ontologydefense response to fungus1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0003824 IEAInterProcatalytic activity
GO:0005524 IEAUniProtATP binding1
GO:0016874 IEAUniProtligase activity1
GO:0016207 IDAUniProt4-coumarate-CoA ligase activity1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0016021 IEAUniProtintegral component of membrane1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000873AMP-dependent synthetase/ligase
IPR025110AMP-binding enzyme, C-terminal domain
IPR020845AMP-binding, conserved site

Mapman id Description
7.8.1.1.Coenzyme metabolism.prenylquinone biosynthesis.4-hydroxybenzoate biosynthesis.p-coumarate:CoA ligase
9.2.1.3.Secondary metabolism.phenolics.p-coumaroyl-CoA biosynthesis.4-coumarate:CoA ligase (4CL)
No SignalP domains detected for this gene.