PLAZA 4.0 Monocots gene overview : AT1G65060

Gene: AT1G65060 (Arabidopsis thaliana)

Curated Summary: encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. mRNA levels are not induced in response to wounding or to fungal infection by P. parasitica. mRNA is expressed in flowers, to a lesser degree in mature leaves and siliques and marginally in seedling roots and bolting stems of mature plants. The catalytic efficiency was in the following (descending) order: p-coumaric acid, caffeic acid, ferulic acid, cinnamic acid and 5-OH-ferulic acid. At4CL3 was unable to use sinapic acid as substrate.

GO term	Evidence(s)	Provider	Description	Source
GO:0008152	IEA	UniProt	metabolic process	1
GO:0010584	IMP	UniProt	pollen exine formation	1
GO:0009411	IEP	Gene Ontology	response to UV	1
GO:0009611	IEP	Gene Ontology	response to wounding	1
GO:0009698	TAS	UniProt	phenylpropanoid metabolic process	1
GO:0050832	IEP	Gene Ontology	defense response to fungus	1

GO term	Evidence(s)	Provider	Description	Source
GO:0003824	IEA	InterPro	catalytic activity
GO:0005524	IEA	UniProt	ATP binding	1
GO:0016874	IEA	UniProt	ligase activity	1
GO:0016207	IDA	UniProt	4-coumarate-CoA ligase activity	1

GO term	Evidence(s)	Provider	Description	Source
GO:0016021	IEA	UniProt	integral component of membrane	1

Experimental Evidence

Electronic Evidence

Computational Reviewed Evidence

InterPro	Description
IPR000873	AMP-dependent synthetase/ligase
IPR025110	AMP-binding enzyme, C-terminal domain
IPR020845	AMP-binding, conserved site

Mapman id	Description
7.8.1.1	.Coenzyme metabolism.prenylquinone biosynthesis.4-hydroxybenzoate biosynthesis.p-coumarate:CoA ligase
9.2.1.3	.Secondary metabolism.phenolics.p-coumaroyl-CoA biosynthesis.4-coumarate:CoA ligase (4CL)

No SignalP domains detected for this gene.