Gene: AT1G51680 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G51680
Transcript Identifier
AT1G51680.1
Gene Type
Coding gene
Location
Chr1 : 19159007-19161464 : negative

Family

Gene family
HOM04M000185
(503 genes in 27 species)
specific family
Subfamily
ORTHO04M000924
(130 genes in 27 species)
specific family
Duplication type
Block duplicate

Descriptions

Curated Summary
encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. In addition to 4-coumarate, it also converts ferulate. The catalytic efficiency was in the following (descending) order: p-coumaric acid, ferulic acid, caffeic acid and 5-OH-ferulic acid. At4CL1 was unable to use sinapic acid as substrate.
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Identifiers

Type Value
Alias4CL.1,4-COUMARATE:COA LIGASE 1,AT4CL1,ARABIDOPSIS THALIANA 4-COUMARATE:COA LIGASE 1
symbol4CL1
tidAT1G51680.1
UniProtQ42524

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0008152 IEAUniProtmetabolic process1
GO:0009411 IEPGene Ontologyresponse to UV1
GO:0009611 IEPGene Ontologyresponse to wounding1
GO:0009620 IEPGene Ontologyresponse to fungus1
GO:0009698 TASUniProtphenylpropanoid metabolic process1
GO:0009699 IEAPLAZA Integrative Orthologyphenylpropanoid biosynthetic processAT3G21230

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0003824 IEAInterProcatalytic activity
GO:0005524 IEAUniProtATP binding1
GO:0016874 IEAUniProtligase activity1
GO:0016207 IDAUniProt4-coumarate-CoA ligase activity1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634 ISMGene Ontologynucleus1
GO:0005737 IDAUniProtcytoplasm1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000873AMP-dependent synthetase/ligase
IPR025110AMP-binding enzyme, C-terminal domain
IPR020845AMP-binding, conserved site

Mapman id Description
7.8.1.1.Coenzyme metabolism.prenylquinone biosynthesis.4-hydroxybenzoate biosynthesis.p-coumarate:CoA ligase
9.2.1.3.Secondary metabolism.phenolics.p-coumaroyl-CoA biosynthesis.4-coumarate:CoA ligase (4CL)
No SignalP domains detected for this gene.