Gene: AT1G50030 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G50030
Transcript Identifier
AT1G50030.1
Gene Type
Coding gene
Location
Chr1 : 18522626-18539619 : negative

Family

Gene family
HOM04M003206
(53 genes in 28 species)
specific family
Subfamily
ORTHO04M004485
(45 genes in 28 species)
specific family

Descriptions

Description
target of rapamycin
Curated Summary
Related to TOR proteins from yeast and mammals, regulators of cell growth in response to nutrient availability. TOR proteins belong to the family of phosphatidylinositol 3-kinase and are targets of the antiproliferative drug rapamycin. AtTOR binds the yeast FKBP12 protein in the presence of Rapamycin, is involved in embryogenesis and is expressed in embryos, endosperm and meristems.
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Identifiers

Type Value
symbolTOR
tidAT1G50030.1
UniProtQ9FR53

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006952 IEAUniProtdefense response1
GO:0009688 IEAUniProtabscisic acid biosynthetic process1
GO:0009734 IEAUniProtauxin-activated signaling pathway1
GO:0009742 IEAUniProtbrassinosteroid mediated signaling pathway1
GO:0009793 IMPUniProtembryo development ending in seed dormancy1
GO:0010507 IMPUniProtnegative regulation of autophagy1
GO:0009303 IMPUniProtrRNA transcription1
GO:0009791 IMPUniProtpost-embryonic development1
GO:0030307 IMPUniProtpositive regulation of cell growth1
GO:0040019 IMPUniProtpositive regulation of embryonic development1
GO:0045893 IMPUniProtpositive regulation of transcription, DNA-templated1
GO:2000234 IMPUniProtpositive regulation of rRNA processing1
GO:0009615 IDA, IMP, UniProtresponse to virus1 2 3 4
GO:0009630 IMPUniProtgravitropism1 2
GO:0009733 IDAUniProtresponse to auxin1 2
GO:0009745 IMPUniProtsucrose mediated signaling1 2
GO:1902661 IMPUniProtpositive regulation of glucose mediated signaling pathway1 2
GO:1901355 IDAUniProtresponse to rapamycin1 2
GO:0050687 IMPUniProtnegative regulation of defense response to virus1 2
GO:0010116 IMPUniProtpositive regulation of abscisic acid biosynthetic process1 2
GO:0010929 IDAUniProtpositive regulation of auxin mediated signaling pathway1 2
GO:1900459 IMPUniProtpositive regulation of brassinosteroid mediated signaling pathway1 2
GO:0006281 IBAUniProtDNA repair
GO:0016032 IEAUniProtviral process

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0016301 IEAInterProkinase activity
GO:0044877 IEAUniProtmacromolecular complex binding1
GO:0004674 IEAUniProtprotein serine/threonine kinase activity1
GO:0005515 IPI, IEAGene Ontologyprotein binding1
GO:0005488 IEAInterProbinding
GO:0005524 IEAUniProtATP binding1
GO:0016303 ISSUniProt1-phosphatidylinositol-3-kinase activity1
GO:0004672 IDAUniProtprotein kinase activity1 2
GO:0000975 IDAUniProtregulatory region DNA binding1
GO:0042802 IPIUniProtidentical protein binding1
GO:0043621 IPIUniProtprotein self-association1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005886 ISMGene Ontologyplasma membrane1
GO:0005634 IDAUniProtnucleus1
GO:0005737 IDAUniProtcytoplasm1
GO:0005844 IDAUniProtpolysome1 2

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000403Phosphatidylinositol 3-/4-kinase, catalytic domain
IPR011989Armadillo-like helical
IPR009076FKBP12-rapamycin binding domain
IPR026683Serine/threonine-protein kinase TOR
IPR003151PIK-related kinase, FAT
IPR003152FATC domain
IPR024585Domain of unknown function DUF3385, target of rapamycin protein
IPR018936Phosphatidylinositol 3/4-kinase, conserved site
IPR014009PIK-related kinase
IPR016024Armadillo-type fold
IPR011009Protein kinase-like domain

Mapman id Description
18.4.7.1.Protein modification.phosphorylation.atypical protein kinase families.protein kinase (PIKK)
27.7.1.1.Multi-process regulation.Target Of Rapamycin (TOR) signalling.TORC complex.phosphatidylinositol kinase component TOR
No SignalP domains detected for this gene.