Gene: AT1G45145 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G45145
Transcript Identifier
AT1G45145.1
Gene Type
Coding gene
Location
Chr1 : 17075264-17076256 : negative

Family

Gene family
HOM04M000254
(386 genes in 29 species)
specific family
Subfamily
ORTHO04M000463
(203 genes in 29 species)
specific family

Descriptions

Description
thioredoxin H-type 5
Curated Summary
encodes a cytosolic thioredoxin that reduces disulfide bridges of target proteins by the reversible formation of a disulfide bridge between two neighboring Cys residues present in the active site. Thioredoxins have been found to regulate a variety of biological reactions in prokaryotic and eukaryotic cells.
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Identifiers

Type Value
AliasATH5,THIOREDOXIN H-TYPE 5,ATTRX5,thioredoxin H-type 5,LIV1,LOCUS OF INSENSITIVITY TO VICTORIN 1,TRX-h5,THIOREDOXIN H-TYPE 5
symbolTRX5
tidAT1G45145.1
UniProtQ39241

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006662 IEAUniProtglycerol ether metabolic process1
GO:0045454 IBA, IEA, UniProtcell redox homeostasis1
GO:0034599 IBAUniProtcellular response to oxidative stress1
GO:0055114 IDA, IEAGene Ontologyoxidation-reduction process1 2
GO:0006979 IEPUniProtresponse to oxidative stress1
GO:0046686 IEPUniProtresponse to cadmium ion1
GO:0010188 IMPUniProtresponse to microbial phytotoxin1
GO:0050832 IMPUniProtdefense response to fungus1
GO:0051259 IEAPLAZA Integrative Orthologyprotein oligomerizationAT5G42980
GO:0009408 IEAPLAZA Integrative Orthologyresponse to heatAT5G42980
GO:0009735 IEAPLAZA Integrative Orthologyresponse to cytokininAT5G42980
GO:0006457 IEAPLAZA Integrative Orthologyprotein foldingAT5G42980
GO:0042542 IEAPLAZA Integrative Orthologyresponse to hydrogen peroxideAT5G42980
GO:0010286 IEAPLAZA Integrative Orthologyheat acclimationAT5G42980

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0015035 IBA, IEA, UniProtprotein disulfide oxidoreductase activity1
GO:0004791 IBAUniProtthioredoxin-disulfide reductase activity1
GO:0047134 IBAUniProtprotein-disulfide reductase activity1
GO:0016671 IDAUniProtoxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor1
GO:0005515 IEAPLAZA Integrative Orthologyprotein bindingAT5G42980

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737 ISMGene Ontologycytoplasm1
GO:0005886 IDAUniProtplasma membrane1
GO:0009506 IDAUniProtplasmodesma1
GO:0048046 IDAUniProtapoplast1
GO:0005829 TASUniProtcytosol1
GO:0016020 IEAPLAZA Integrative OrthologymembraneAT5G42980
GO:0005618 IEAPLAZA Integrative Orthologycell wallAT5G42980
GO:0005739 IEAPLAZA Integrative OrthologymitochondrionAT5G42980
GO:0009507 IEAPLAZA Integrative OrthologychloroplastAT5G42980
GO:0005773 IEAPLAZA Integrative OrthologyvacuoleAT5G42980
GO:0005794 IEAPLAZA Integrative OrthologyGolgi apparatusAT5G42980
GO:0009570 IEAPLAZA Integrative Orthologychloroplast stromaAT5G42980

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR005746Thioredoxin
IPR013766Thioredoxin domain
IPR017937Thioredoxin, conserved site
IPR012336Thioredoxin-like fold

Mapman id Description
10.6.1.Redox homeostasis.cytosol/mitochondrion/nucleus redox homeostasis.H-type thioredoxin
18.7.2.Protein modification.S-nitrosylation.protein-S-nitrosothiol reductase (TRX5)
No SignalP domains detected for this gene.