Gene: AT1G26830 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G26830
Transcript Identifier
AT1G26830.1
Gene Type
Coding gene
Location
Chr1 : 9296063-9298374 : positive

Family

Gene family
HOM04M000392
(290 genes in 29 species)
specific family
Subfamily
ORTHO04M002546
(68 genes in 29 species)
specific family
Duplication type
Block duplicate

Descriptions

Description
cullin 3
Curated Summary
Cullin, putative, similar to Cullin homolog 3 (CUL-3) SP:Q13618, GI:3639052 from (Homo sapiens); contains Pfam profile PF00888: Cullin family. Interacts with other components of E3 ligase complex suggesting it functions in RUB-modification. Forms complexes with BTB domain proteins forming a novel class of E3-based ubiquitin protein-ligase complexes. Mutant is early flowering and has a reduced sensitivity to far-red light. cul3a/cul3b homozygous/heterozygous plants are embryo lethal.
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Identifiers

Type Value
AliasATCUL3A,cullin 3A,ATCUL3,cullin 3,CUL3A,cullin 3A
symbolCUL3
tidAT1G26830.1
UniProtQ9ZVH4

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006511 TAS, IEAGene Ontologyubiquitin-dependent protein catabolic process1
GO:0042787 IBAUniProtprotein ubiquitination involved in ubiquitin-dependent protein catabolic process1
GO:0009639 IMPUniProtresponse to red or far red light1
GO:0009911 IMPUniProtpositive regulation of flower development1
GO:0009793 IGIGene Ontologyembryo development ending in seed dormancy1
GO:0009960 IGIGene Ontologyendosperm development1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0031625 IBA, IEA, UniProtubiquitin protein ligase binding1
GO:0004842 ISSGene Ontologyubiquitin-protein transferase activity1
GO:0061630 IBAGene Ontologyubiquitin protein ligase activity1
GO:0005515 IPIGene Ontologyprotein binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634 ISMGene Ontologynucleus1
GO:0031461 IBAUniProtcullin-RING ubiquitin ligase complex1
GO:0000151 TASGene Ontologyubiquitin ligase complex1
GO:0019005 IPIGene OntologySCF ubiquitin ligase complex1
GO:0005829 IDAUniProtcytosol1

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR011991Winged helix-turn-helix DNA-binding domain
IPR019559Cullin protein, neddylation domain
IPR001373Cullin, N-terminal
IPR016158Cullin homology
IPR016159Cullin repeat-like-containing domain

Mapman id Description
19.2.2.8.2.1.Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.CUL3-BTB E3 ligase complexes.scaffold component CUL3
No SignalP domains detected for this gene.