Gene: AT1G17440 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G17440
Transcript Identifier
AT1G17440.1
Gene Type
Coding gene
Location
Chr1 : 5984407-5987663 : negative

Family

Gene family
HOM04M002091
(76 genes in 29 species)
specific family

Descriptions

Description
Transcription initiation factor TFIID subunit A
Curated Summary
Encodes one of two Arabidopsis proteins with similarity to the TBP-associated factor TAF12. The gene product is an EIN3-interacting TFIID transcription factor required for proper ethylene response, including ERF1 induction. Loss of function mutants show enhanced response to ethylene. Located in nucleus and expressed throughout the plant. Required for ERF1 expression. Cytokinin-hypersensitive 1 (CKH1) mutants are characterized by rapidly growing calli with a green color at low levels of cytokinins, which are insufficient to induce such cytokinin responses in wild-type explants. It is hypothesized that CKH1 acts as a negative regulator of cytokinin signaling in Arabidopsis.
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Identifiers

Type Value
AliasCKH1,CYTOKININ-HYPERSENSITIVE 1,TAF12B,TBP-ASSOCIATED FACTOR 12B
full_nameENHANCED ETHYLENE RESPONSE 4
symbolEER4
tidAT1G17440.1
UniProtQ940A7

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006352 IEA, ISSUniProtDNA-templated transcription, initiation1
GO:0006355 IEAUniProtregulation of transcription, DNA-templated1
GO:0006413 IEAGene Ontologytranslational initiation1
GO:0043966 IBAUniProthistone H3 acetylation1
GO:0051123 IBAUniProtRNA polymerase II transcriptional preinitiation complex assembly1
GO:0009736 IMPUniProtcytokinin-activated signaling pathway1
GO:0009867 IMPUniProtjasmonic acid mediated signaling pathway1
GO:0010104 IMPUniProtregulation of ethylene-activated signaling pathway1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0046982 IEAUniProtprotein heterodimerization activity1
GO:0001102 IBAUniProtRNA polymerase II activating transcription factor binding1
GO:0003677 IBAUniProtDNA binding1
GO:0003743 IEAUniProttranslation initiation factor activity1
GO:0004402 IBAGene Ontologyhistone acetyltransferase activity1
GO:0017025 IBAUniProtTBP-class protein binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005669 IBA, IEAISS, UniProttranscription factor TFIID complex1 2
GO:0000124 IBAUniProtSAGA complex1
GO:0005634 IDA, ISM, UniProtnucleus1 2

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003228Transcription initiation factor TFIID, subunit 12
IPR009072Histone-fold

Mapman id Description
15.3.4.3.5.RNA biosynthesis.RNA polymerase II-dependent transcription.SAGA transcription co-activator complex.TAF transcription co-activator module.component TAF12
15.3.5.3.12.RNA biosynthesis.RNA polymerase II-dependent transcription.transcription initiation.TFIId basal transcription regulation complex.component TAF12
No SignalP domains detected for this gene.