Gene: AT1G13980 (Arabidopsis thaliana)

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Gene Identifier
AT1G13980
Transcript Identifier
AT1G13980.1
Gene Type
Coding gene
Location
Chr1 : 4789587-4794397 : positive

Family

Gene family
HOM04M000422
(271 genes in 29 species)
specific family
Subfamily
ORTHO04M001556
(92 genes in 29 species)
specific family

Descriptions

Description
sec7 domain-containing protein
Curated Summary
Encodes a GDP/GTP exchange factor for small G-proteins of the ADP ribosylation factor (RAF) class, and as regulator of intracellular trafficking. Homologous to Sec7p and YEC2 from yeast. Involved in the specification of apical-basal pattern formation. Essential for cell division, expansion and adhesion. It appears that heteotypic binding between the DCB and C-terminal domains of two GNOM proteins is required for membrane association, however, GNOM appears to exist predominantly as a heterodimer formed through DCB-DCB interactions.
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Identifiers

Type Value
AliasEMB30,EMBRYO DEFECTIVE 30,VAN7,VASCULAR NETWORK 7
full_nameGNOM
symbolGN
tidAT1G13980.1
UniProtQ42510

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0032012 IEAUniProtregulation of ARF protein signal transduction1
GO:0015031 IEAUniProtprotein transport1
GO:0010087 IMPUniProtphloem or xylem histogenesis1
GO:0007155 IMPUniProtcell adhesion1
GO:0071555 IMPUniProtcell wall organization1
GO:0016192 IMPUniProtvesicle-mediated transport1
GO:0032509 IMPUniProtendosome transport via multivesicular body sorting pathway1
GO:0048209 TASUniProtregulation of vesicle targeting, to, from or within Golgi1
GO:0001736 IGIUniProtestablishment of planar polarity1
GO:0048765 IGIUniProtroot hair cell differentiation1
GO:0010311 IMPUniProtlateral root formation1
GO:0010540 IMPUniProtbasipetal auxin transport1
GO:0006897 IMPUniProtendocytosis1
GO:0000911 IMPUniProtcytokinesis by cell plate formation1
GO:0009793 IMPUniProtembryo development ending in seed dormancy1
GO:0009826 IMPUniProtunidimensional cell growth1
GO:0009880 IMPUniProtembryonic pattern specification1
GO:0009942 IMPUniProtlongitudinal axis specification1
GO:0010274 IMPUniProthydrotropism

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005086 IDA, IEA, UniProtARF guanyl-nucleotide exchange factor activity1
GO:0005488 IEAInterProbinding
GO:0010292 IGIGene OntologyGTP:GDP antiporter activity1
GO:0005515 IPIGene Ontologyprotein binding1
GO:0042802 IPIUniProtidentical protein binding1
GO:0042803 IPIUniProtprotein homodimerization activity1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737 ISMGene Ontologycytoplasm1
GO:0005802 IBAUniProttrans-Golgi network1
GO:0005829 IEAUniProtcytosol1
GO:0010008 IEAUniProtendosome membrane1
GO:0005768 IDAUniProtendosome1
GO:0005886 IDAUniProtplasma membrane1

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR011989Armadillo-like helical
IPR023394Sec7 domain, alpha orthogonal bundle
IPR032691Guanine nucleotide exchange factor, N-terminal
IPR000904Sec7 domain
IPR016024Armadillo-type fold

Mapman id Description
22.3.3.1.Vesicle trafficking.Coat protein I (COPI) coatomer machinery.ARF-GTPase guanyl-nucleotide exchange factor (ARF-GEF) activities.ARF-GEF factor (GBF)
No SignalP domains detected for this gene.