Gene: AT1G12550 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G12550
Transcript Identifier
AT1G12550.1
Gene Type
Coding gene
Location
Chr1 : 4274649-4275831 : positive

Family

Gene family
HOM04M000652
(195 genes in 28 species)
specific family
Subfamily
ORTHO04M000682
(159 genes in 29 species)
specific family

Descriptions

Description
D-isomer specific 2-hydroxyacid dehydrogenase family protein
Curated Summary
Encodes a hydroxypyruvate reductase that reduces HP to glycerate and shows even more activity with glyoxylate, a more upstream intermediate of the photorespiratory cycle. It is likely targeted to the chloroplast where it could provide a compensatory bypass for the reduction of HP and glyoxylate within this compartment.
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Identifiers

Type Value
full_namehydroxypyruvate reductase 3
symbolHPR3
tidAT1G12550.1
UniProtQ9LE33

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0055114 IDA, IEAGene Ontologyoxidation-reduction process1 2
GO:0008152 IEAInterPrometabolic process
GO:0009854 IEAUniProtoxidative photosynthetic carbon pathway1
GO:0009853 IMPUniProtphotorespiration1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0051287 IEAUniProtNAD binding1
GO:0016616 IEAInterProoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0016491 ISSGene Ontologyoxidoreductase activity1
GO:0016618 IDAUniProthydroxypyruvate reductase activity1
GO:0030267 IDAUniProtglyoxylate reductase (NADP) activity1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737 ISMGene Ontologycytoplasm1
GO:0005829 IBAUniProtcytosol

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR006140D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
IPR006139D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
IPR016040NAD(P)-binding domain

Mapman id Description
50.1.1.Enzyme classification.EC_1 oxidoreductases.EC_1.1 oxidoreductase acting on CH-OH group of donor
No SignalP domains detected for this gene.