Gene: AT1G08030 (Arabidopsis thaliana)

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Gene Identifier
AT1G08030
Transcript Identifier
AT1G08030.1
Gene Type
Coding gene
Location
Chr1 : 2489575-2492741 : negative

Family

Gene family
HOM04M003793
(46 genes in 28 species)
specific family

Descriptions

Description
tyrosylprotein sulfotransferase
Curated Summary
Encodes a tyrosylprotein sulfotransferase (TPST). This protein is a 500-aa type I transmembrane protein that shows no sequence similarity to animal TPSTs. Activity confirmed by protein expression in yeast. TPST is expressed throughout the plant body, and the highest levels of expression are in the root apical meristem. TPST acts in the auxin pathway to maintain postembryonic root stem cell niche by defining the expression of the PLETHORA stem cell transcription factor genes. A loss-of-function mutant TPST displayed a marked dwarf phenotype accompanied by stunted roots, pale green leaves, reduction in higher order veins, early senescence, and a reduced number of flowers and siliques.
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Identifiers

Type Value
AliasAQC1,active quiescent center1,HPS7,hypersensitive to Pi starvation 7
symbolTPST
tidAT1G08030.1
UniProtQ3EDG5

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0015015 IBAUniProtheparan sulfate proteoglycan biosynthetic process, enzymatic modification1
GO:0009733 IEPUniProtresponse to auxin1
GO:0010082 IMPUniProtregulation of root meristem growth1
GO:0010468 IMPUniProtregulation of gene expression1
GO:0019827 IMPUniProtstem cell population maintenance1
GO:0045087 IMPUniProtinnate immune response1
GO:0010366 IMPUniProtnegative regulation of ethylene biosynthetic process1 2
GO:0055070 IMPUniProtcopper ion homeostasis1 2

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0008146 IEAInterProsulfotransferase activity
GO:0017095 IBAUniProtheparan sulfate 6-O-sulfotransferase activity1
GO:0008476 IDAUniProtprotein-tyrosine sulfotransferase activity1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0016021 IEAUniProtintegral component of membrane1
GO:0000139 IEAUniProtGolgi membrane1
GO:0005794 IDAUniProtGolgi apparatus1
GO:0005768 IDAUniProtendosome1
GO:0005802 IDAUniProttrans-Golgi network1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR010635Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase
IPR005331Sulfotransferase

Mapman id Description
18.6.1.Protein modification.tyrosine sulfation.tyrosyl protein sulfotransferase
No SignalP domains detected for this gene.