Gene: AT1G01040 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G01040
Transcript Identifier
AT1G01040.1
Gene Type
Coding gene
Location
Chr1 : 23519-31079 : positive

Family

Gene family
HOM04M000371
(307 genes in 28 species)
specific family
Subfamily
ORTHO04M000440
(210 genes in 28 species)
specific family

Descriptions

Description
dicer-like 1
Curated Summary
Encodes a Dicer homolog. Dicer is a RNA helicase involved in microRNA processing. Mutations in this locus can result in embryo lethality. Embryo shape at seed maturity is globular-elongate. Other mutants convert the floral meristems to an indeterminate state, others yet show defects in ovule development. mRNA is expressed in all shoot tissues. DCL1 is able to produce miRNAs and siRNAs.
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Identifiers

Type Value
AliasASU1,ABNORMAL SUSPENSOR 1,ATDCL1,DICER-LIKE 1,CAF,CARPEL FACTORY,EMB60,EMBRYO DEFECTIVE 60,EMB76,EMBRYO DEFECTIVE 76,SIN1,SHORT INTEGUMENTS 1,SUS1,SUSPENSOR 1
symbolDCL1
tidAT1G01040.1
UniProtQ9SP32

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006396 IEA, ISS, UniProtRNA processing1
GO:0016075 IEAUniProtrRNA catabolic process1
GO:0010098 IMPGene Ontologysuspensor development1
GO:0000911 IMPUniProtcytokinesis by cell plate formation1
GO:0035279 IMPUniProtmRNA cleavage involved in gene silencing by miRNA1
GO:0031053 TASUniProtprimary miRNA processing1
GO:0010267 IMPUniProtproduction of ta-siRNAs involved in RNA interference1
GO:0035196 IGIGene Ontologyproduction of miRNAs involved in gene silencing by miRNA1
GO:0009616 IMPUniProtvirus induced gene silencing1
GO:0010599 IMPUniProtproduction of lsiRNA involved in RNA interference1
GO:2000034 IMPUniProtregulation of seed maturation1
GO:0048317 IMPUniProtseed morphogenesis1 2
GO:0009880 IMPUniProtembryonic pattern specification1
GO:0009908 TASUniProtflower development1
GO:0010228 IMPUniProtvegetative to reproductive phase transition of meristem1
GO:0031047 IEAUniProtgene silencing by RNA

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004525 IBA, IEA, ISS, UniProtribonuclease III activity1 2
GO:0003723 IEAUniProtRNA binding
GO:0005515 IPI, IEAGene Ontologyprotein binding1
GO:0016891 IEAUniProtendoribonuclease activity, producing 5'-phosphomonoesters
GO:0003677 IEAUniProtDNA binding1
GO:0005524 IEAUniProtATP binding1
GO:0016787 IEAInterProhydrolase activity
GO:0004386 IEAUniProthelicase activity1
GO:0008026 ISSGene OntologyATP-dependent helicase activity1
GO:0046872 IEAUniProtmetal ion binding1
GO:0003725 IDAUniProtdouble-stranded RNA binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634 IDA, IEA, ISM, UniProtnucleus1 2
GO:0010445 IDAUniProtnuclear dicing body1
GO:0005737 IBAUniProtcytoplasm
GO:0016442 IBAUniProtRISC complex

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000999Ribonuclease III domain
IPR011907Ribonuclease III
IPR003100PAZ domain
IPR005034Dicer dimerisation domain
IPR001650Helicase, C-terminal
IPR006935Helicase/UvrB, N-terminal
IPR014720Double-stranded RNA-binding domain
IPR014001Helicase superfamily 1/2, ATP-binding domain
IPR027417P-loop containing nucleoside triphosphate hydrolase

Mapman id Description
16.10.2.1.1.RNA processing.mRNA silencing.miRNA pathway.DCL1-HYL1 miRNA biogenesis complex.endoribonuclease component DCL1
No SignalP domains detected for this gene.