Gene: AT5G05980 (Arabidopsis thaliana)

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Gene Identifier
AT5G05980
Transcript Identifier
AT5G05980.1
Gene Type
Coding gene
Location
Chr5 : 1799738-1804441 : negative

Family Information

Homologous gene family
HOM04x5M002239
(113 genes in 39 species)
specific family
Orthologous gene family
ORTHO04x5M002625
(104 genes in 39 species)
specific family
Duplication type
Block duplicate

Descriptions

Description
DHFS-FPGS homolog B
Curated Summary
Encodes one of the three folylpolyglutamate synthetase isoforms (FPGSs): FPGS1 (At5g05980, plastidic), FPGS2 (At3g10160, mitochondrial) and FPGS3 (At3g55630, cytosolic).
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Identifiers

Type Value
AliasATDFB,DHFS-FPGS homolog B,FPGS1,folylpolyglutamate synthetase 1
Dbxrefgene:2153638,UniProt:F4K2A1
symbolDFB
tidAT5G05980.1

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009058
IEA
InterProbiosynthetic process
GO:0009396
IBA
Gene Ontologyfolic acid-containing compound biosynthetic process1
GO:0009396
IEA
InterProfolic acid-containing compound biosynthetic process
GO:0006730
TAS
Gene Ontologyone-carbon metabolic process2 3
GO:0010449
IMP
Gene Ontologyroot meristem growth4 5
GO:0046901
IMP
IBA
Gene Ontologytetrahydrofolylpolyglutamate biosynthetic process1 4 5
GO:0048364
IMP
Gene Ontologyroot development4 5
GO:0048767
IMP
Gene Ontologyroot hair elongation4 5
GO:1904961
IMP
Gene Ontologyquiescent center organization4 5

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005524
IEA
InterProATP binding
GO:0016874
IEA
InterProligase activity
GO:0004326
IMP, IGI
IBA
Gene Ontologytetrahydrofolylpolyglutamate synthase activity1 2 3 6 7
GO:0004326
IEA
InterProtetrahydrofolylpolyglutamate synthase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009570
IDA
Gene Ontologychloroplast stroma2 3
GO:0005829
IDA
IBA
Gene Ontologycytosol1 8 9
GO:0005737
IBA
Gene Ontologycytoplasm1
GO:0005739
IBA
Gene Ontologymitochondrion1

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR036615Mur ligase, C-terminal domain superfamily
IPR036565Mur-like, catalytic domain superfamily
IPR023600Folylpolyglutamate synthase, eukaryota
IPR001645Folylpolyglutamate synthetase
IPR013221Mur ligase, central
IPR018109Folylpolyglutamate synthetase, conserved site

Mapman id Description
7.5.6Coenzyme metabolism.tetrahydrofolate biosynthesis.folyl-polyglutamate synthetase