Gene: AT4G34710 (Arabidopsis thaliana)

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Gene Identifier
AT4G34710
Transcript Identifier
AT4G34710.1
Gene Type
Coding gene
Location
Chr4 : 16560315-16562450 : negative

Family Information

Homologous gene family
HOM04x5M002107
(119 genes in 37 species)
specific family
Orthologous gene family
ORTHO04x5M003566
(84 genes in 37 species)
specific family
Duplication type
Block duplicate

Descriptions

Description
arginine decarboxylase 2
Curated Summary
encodes a arginine decarboxylase (ADC), a rate-limiting enzyme that catalyzes the first step of polyamine (PA) biosynthesis via ADC pathway in Arabidopsis thaliana. Arabidopsis genome has two ADC paralogs, ADC1 and ADC2. ADC2 is stress-inducible (osmotic stress). Double mutant analysis showed that ADC genes are essential for the production of PA, and are required for normal seed development. Overexpression causes phenotypes similar to GA-deficient plants and these plants show reduced levels of GA due to lower expression levels of AtGA20ox1, AtGA3ox3 and AtGA3ox1.
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Identifiers

Type Value
AliasATADC2,SPE2
DbxrefPMID:11351099,PMID:15634198,gene:2139628,UniProt:O23141
symbolADC2
tidAT4G34710.1

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006527
IEA
Gene Ontologyarginine catabolic process1
GO:0006527
IEA
InterProarginine catabolic process
GO:0008295
IEA
Gene Ontologyspermidine biosynthetic process2
GO:0008295
IEA
InterProspermidine biosynthetic process
GO:0006596
IMP
Gene Ontologypolyamine biosynthetic process3 4
GO:0006970
IMP
Gene Ontologyresponse to osmotic stress3 4
GO:0009611
IEP
Gene Ontologyresponse to wounding5 6
GO:0009737
IEP
Gene Ontologyresponse to abscisic acid5 6
GO:0009753
IEP
Gene Ontologyresponse to jasmonic acid5 6
GO:0009651
IMP
Gene Ontologyresponse to salt stress7 8
GO:0006979
IEP
Gene Ontologyresponse to oxidative stress9 10
GO:0009446
IMP
Gene Ontologyputrescine biosynthetic process11 12
GO:0048316
IGI
Gene Ontologyseed development11 12
GO:0009409
IMP
Gene Ontologyresponse to cold13 14
GO:0080167
IEP
Gene Ontologyresponse to karrikin15 16
GO:0033388
IBA
Gene Ontologyputrescine biosynthetic process from arginine17
GO:0009445
ISO
PLAZA Integrative Orthologyputrescine metabolic process Solyc01g110440.2

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008792
IMP
IBA
Gene Ontologyarginine decarboxylase activity3 4 17
GO:0008792
IEA
InterProarginine decarboxylase activity
GO:0003824
IEA
InterProcatalytic activity
GO:0005515
IPI
Gene Ontologyprotein binding18 19
GO:0042803
IPI
Gene Ontologyprotein homodimerization activity18 19

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISM
Gene Ontologynucleus20
GO:0005829
IDA
Gene Ontologycytosol18 19
GO:0009507
IDA
Gene Ontologychloroplast18 19

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002985Arginine decarboxylase
IPR009006Alanine racemase/group IV decarboxylase, C-terminal
IPR029066PLP-binding barrel
IPR022644Orn/DAP/Arg decarboxylase 2, N-terminal
IPR000183Ornithine/DAP/Arg decarboxylase
IPR022653Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site
IPR022657Orn/DAP/Arg decarboxylase 2, conserved site

Mapman id Description
8.1.1.1Polyamine metabolism.putrescine biosynthesis.plastidial/nuclear pathway.arginine decarboxylase