Gene: AT3G10160 (Arabidopsis thaliana)

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Gene Identifier
AT3G10160
Transcript Identifier
AT3G10160.1
Gene Type
Coding gene
Location
Chr3 : 3139588-3143949 : negative

Family Information

Homologous gene family
HOM04x5M002239
(113 genes in 39 species)
specific family
Orthologous gene family
ORTHO04x5M002625
(104 genes in 39 species)
specific family

Descriptions

Description
DHFS-FPGS homolog C
Curated Summary
Encodes a protein with tetrahydrofolylpolyglutamate synthase activity that is located in the mitochondrial matrix. One of the three folylpolyglutamate synthetase isoforms (FPGSs): FPGS1 (At5g05980, plastidic), FPGS2 (At3g10160, mitochondrial) and FPGS3 (At3g55630, cytosolic).
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Identifiers

Type Value
AliasATDFC,A. THALIANA DHFS-FPGS HOMOLOG C,FPGS2,folylpolyglutamate synthetase 2
Dbxrefgene:2100047,UniProt:F4J2K2
symbolDFC
tidAT3G10160.1

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009058
IEA
InterProbiosynthetic process
GO:0009396
IBA
Gene Ontologyfolic acid-containing compound biosynthetic process1
GO:0009396
IEA
InterProfolic acid-containing compound biosynthetic process
GO:0006730
TAS
Gene Ontologyone-carbon metabolic process2 3
GO:0009853
IMP
Gene Ontologyphotorespiration4 5
GO:0090351
IMP
Gene Ontologyseedling development4 5
GO:0046901
IBA
Gene Ontologytetrahydrofolylpolyglutamate biosynthetic process1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005524
IEA
InterProATP binding
GO:0004326
IMP, IGI
IBA
Gene Ontologytetrahydrofolylpolyglutamate synthase activity1 2 3 6 7
GO:0004326
IEA
InterProtetrahydrofolylpolyglutamate synthase activity
GO:0016874
IEA
InterProligase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005759
IDA
Gene Ontologymitochondrial matrix2 3
GO:0005829
IBA
Gene Ontologycytosol1
GO:0005739
IBA
Gene Ontologymitochondrion1
GO:0005737
IBA
Gene Ontologycytoplasm1

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR036565Mur-like, catalytic domain superfamily
IPR001645Folylpolyglutamate synthetase
IPR013221Mur ligase, central
IPR018109Folylpolyglutamate synthetase, conserved site
IPR036615Mur ligase, C-terminal domain superfamily

Mapman id Description
7.5.6Coenzyme metabolism.tetrahydrofolate biosynthesis.folyl-polyglutamate synthetase