Gene: AT2G16500 (Arabidopsis thaliana)

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Gene Identifier
AT2G16500
Transcript Identifier
AT2G16500.1
Gene Type
Coding gene
Location
Chr2 : 7150796-7152904 : negative

Family Information

Homologous gene family
HOM04x5M002107
(119 genes in 37 species)
specific family
Orthologous gene family
ORTHO04x5M003566
(84 genes in 37 species)
specific family
Duplication type
Block duplicate

Descriptions

Description
arginine decarboxylase 1
Curated Summary
encodes a arginine decarboxylase (ADC), a rate-limiting enzyme that catalyzes the first step of polyamine (PA) biosynthesis via ADC pathway in Arabidopsis thaliana. Arabidopsis genome has two ADC paralogs, ADC1 and ADC2. Double mutant analysis showed that ADC genes are essential for the production of PA, and are required for normal seed development. Promoter region of ADC1 contains 742-bp AT-rich transposable element, called AtATE, that belongs to the MITE families of repetitive elements.
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Identifiers

Type Value
AliasARGDC,ARGDC1,SPE1
DbxrefPMID:15634198,gene:2045110,UniProt:Q9SI64
symbolADC1
tidAT2G16500.1

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006527
IEA
Gene Ontologyarginine catabolic process1
GO:0006527
IEA
InterProarginine catabolic process
GO:0008295
IEA
Gene Ontologyspermidine biosynthetic process2
GO:0008295
IEA
InterProspermidine biosynthetic process
GO:0009651
IMP
Gene Ontologyresponse to salt stress3 4
GO:0006979
IEP
Gene Ontologyresponse to oxidative stress5 6
GO:0048316
IGI
Gene Ontologyseed development7 8
GO:0009409
IMP
Gene Ontologyresponse to cold9 10
GO:0006596
IMP
Gene Ontologypolyamine biosynthetic process11 12
GO:0033388
IBA
Gene Ontologyputrescine biosynthetic process from arginine13
GO:0009737
ISO
PLAZA Integrative Orthologyresponse to abscisic acid AT4G34710
GO:0006970
ISO
PLAZA Integrative Orthologyresponse to osmotic stress AT4G34710
GO:0009611
ISO
PLAZA Integrative Orthologyresponse to wounding AT4G34710
GO:0009446
ISO
PLAZA Integrative Orthologyputrescine biosynthetic process AT4G34710
GO:0080167
ISO
PLAZA Integrative Orthologyresponse to karrikin AT4G34710
GO:0009445
ISO
PLAZA Integrative Orthologyputrescine metabolic process Solyc01g110440.2
GO:0009753
ISO
PLAZA Integrative Orthologyresponse to jasmonic acid AT4G34710

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008792
IBA
NAS
Gene Ontologyarginine decarboxylase activity13 14
GO:0008792
IEA
InterProarginine decarboxylase activity
GO:0003824
IEA
InterProcatalytic activity
GO:0005515
IPI
Gene Ontologyprotein binding15 16
GO:0042803
IPI
Gene Ontologyprotein homodimerization activity15 16

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009507
IDA
ISM
Gene Ontologychloroplast15 16 17
GO:0005829
IDA
Gene Ontologycytosol15 16

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002985Arginine decarboxylase
IPR009006Alanine racemase/group IV decarboxylase, C-terminal
IPR029066PLP-binding barrel
IPR022644Orn/DAP/Arg decarboxylase 2, N-terminal
IPR000183Ornithine/DAP/Arg decarboxylase
IPR022653Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site
IPR022657Orn/DAP/Arg decarboxylase 2, conserved site

Mapman id Description
8.1.1.1Polyamine metabolism.putrescine biosynthesis.plastidial/nuclear pathway.arginine decarboxylase