Gene: AT1G50500 (Arabidopsis thaliana)

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Gene Identifier
AT1G50500
Transcript Identifier
AT1G50500.1
Gene Type
Coding gene
Location
Chr1 : 18708217-18715597 : negative

Family Information

Homologous gene family
HOM04x5M004483
(63 genes in 39 species)
specific family
Orthologous gene family
ORTHO04x5M005884
(59 genes in 39 species)
specific family

Descriptions

Description
Membrane trafficking VPS53 family protein
Curated Summary
encodes a member of VPS53 family protein involved in the retrograde trafficking of vesicles to the late Golgi. Mutants in this gene are more sensitive to heat and osmotic stress.
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Identifiers

Type Value
AliasATVPS53,ARABIDOPSIS THALIANA VPS53 HOMOLOG,VPS53
full_nameHEAT-INTOLERANT 1
DbxrefPMID:14671022,PMID:18583349,PMID:21166475,gene:3687845,UniProt:Q0WQF4
symbolHIT1
tidAT1G50500.1

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0042147
IBA
IEA
Gene Ontologyretrograde transport, endosome to Golgi1 2
GO:0042147
IEA
InterProretrograde transport, endosome to Golgi
GO:0015031
IEA
Gene Ontologyprotein transport3
GO:0006890
ISS
Gene Ontologyretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum4 5
GO:0006970
IMP
Gene Ontologyresponse to osmotic stress4 5
GO:0009408
IMP
Gene Ontologyresponse to heat4 5
GO:0007009
IMP
Gene Ontologyplasma membrane organization6 7
GO:0010286
IMP
Gene Ontologyheat acclimation6 7

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Gene Ontologyprotein binding6 7

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000938
IDA
IBA
IEA
Gene OntologyGARP complex1 2 6 7
GO:0000938
IEA
InterProGARP complex
GO:0005794
ISM
Gene OntologyGolgi apparatus8
GO:0005886
ISM
Gene Ontologyplasma membrane8
GO:0010008
IEA
Gene Ontologyendosome membrane9
GO:0005739
IDA
Gene Ontologymitochondrion10 11
GO:0005829
RCA
Gene Ontologycytosol12 13
GO:0000139
IDA
Gene OntologyGolgi membrane6 7

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR039766Vacuolar protein sorting-associated protein 53
IPR007234Vps53-like, N-terminal

Mapman id Description
22.6.1.3Vesicle trafficking.target membrane tethering.GARP/EARP (Golgi-/Endosome-Associated-Retrograde-Protein) complexes.component VPS53/HIT1