Gene: AT1G29690 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G29690
Transcript Identifier
AT1G29690.1
Gene Type
Coding gene
Location
Chr1 : 10379310-10381861 : negative

Family Information

Homologous gene family
HOM04x5M000599
(331 genes in 37 species)
specific family
Orthologous gene family
ORTHO04x5M003635
(83 genes in 37 species)
specific family

Descriptions

Description
MAC/Perforin domain-containing protein
Curated Summary
Encodes a protein containing a domain with significant homology to the MACPF (membrane attack complex and perforin) domain of complements and perforin proteins that are involved in innate immunity in animals. Transgenic cad1-1 mutant plants show lesions seen in the hypersensitive response, as well as a spontaneous activation of expression of pathogenesis-related genes and leading to a 32-fold increase in salicylic acid (SA). CAD1 is postulated to act as a negative regulator controlling SA-mediated pathway of programmed cell death in plant immunity.
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Identifiers

Type Value
AliasNSL2,necrotic spotted lesion 2
full_nameconstitutively activated cell death 1
DbxrefPMID:16960394,gene:2013672,UniProt:Q9C7N2
symbolCAD1
tidAT1G29690.1

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006955
IMP
IBA
Gene Ontologyimmune response1 2 3
GO:0008219
IMP
Gene Ontologycell death2 3
GO:0009626
IMP
IBA
Gene Ontologyplant-type hypersensitive response1 2 3
GO:0010337
IMP
Gene Ontologyregulation of salicylic acid metabolic process2 3

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
IBA
Gene Ontologyplasma membrane1

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR020864Membrane attack complex component/perforin (MACPF) domain

Mapman id Description
35.1not assigned.annotated